Impact of hyper- and hypothermia on cellular and whole-body physiology

Abstract The incidence of heat-related illnesses and heatstroke continues to rise amidst global warming. Hyperthermia triggers inflammation, coagulation, and progressive multiorgan dysfunction, and, at levels above 40 °C, can even lead to cell death. Blood cells, particularly granulocytes and platel...

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Bibliographic Details
Main Authors: Toshiaki Iba, Yutaka Kondo, Cheryl L. Maier, Julie Helms, Ricard Ferrer, Jerrold H. Levy
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Intensive Care
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Online Access:https://doi.org/10.1186/s40560-024-00774-8
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