Susceptibility of calf lung slice cultures to H5N1 influenza virus
The current outbreak of HPAI H5N1 virus infections in dairy cattle in the USA underscores the need for easily accessible methods to rapidly assess host susceptibility for infection with known and emerging influenza viruses. Here we show that ex vivo lung slice cultures from calves provide a useful m...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | Emerging Microbes and Infections |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2024.2432368 |
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| _version_ | 1850164855570432000 |
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| author | Kate Guilfoyle Monica Mirolo Geert van Amerongen Guido van der Net Mara Sophie Lombardo Theresa Störk Guus Rimmelzwaan Martin Ludlow Albert Osterhaus |
| author_facet | Kate Guilfoyle Monica Mirolo Geert van Amerongen Guido van der Net Mara Sophie Lombardo Theresa Störk Guus Rimmelzwaan Martin Ludlow Albert Osterhaus |
| author_sort | Kate Guilfoyle |
| collection | DOAJ |
| description | The current outbreak of HPAI H5N1 virus infections in dairy cattle in the USA underscores the need for easily accessible methods to rapidly assess host susceptibility for infection with known and emerging influenza viruses. Here we show that ex vivo lung slice cultures from calves provide a useful method to rapidly screen host susceptibility to a range of influenza A viruses. |
| format | Article |
| id | doaj-art-2b132e47cf4a42488187bf2ca230405a |
| institution | OA Journals |
| issn | 2222-1751 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-2b132e47cf4a42488187bf2ca230405a2025-08-20T02:21:52ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512025-12-0114110.1080/22221751.2024.2432368Susceptibility of calf lung slice cultures to H5N1 influenza virusKate Guilfoyle0Monica Mirolo1Geert van Amerongen2Guido van der Net3Mara Sophie Lombardo4Theresa Störk5Guus Rimmelzwaan6Martin Ludlow7Albert Osterhaus8Preclinical Speciality Services, Cerba Research (formerly Viroclinics Xplore), Schaijk, The NetherlandsResearch Center for Emerging Infection and zoonoses, University of Veterinary Medicine Hannover, Hannover, GermanyPreclinical Speciality Services, Cerba Research (formerly Viroclinics Xplore), Schaijk, The NetherlandsPreclinical Speciality Services, Cerba Research (formerly Viroclinics Xplore), Schaijk, The NetherlandsResearch Center for Emerging Infection and zoonoses, University of Veterinary Medicine Hannover, Hannover, GermanyResearch Center for Emerging Infection and zoonoses, University of Veterinary Medicine Hannover, Hannover, GermanyResearch Center for Emerging Infection and zoonoses, University of Veterinary Medicine Hannover, Hannover, GermanyResearch Center for Emerging Infection and zoonoses, University of Veterinary Medicine Hannover, Hannover, GermanyResearch Center for Emerging Infection and zoonoses, University of Veterinary Medicine Hannover, Hannover, GermanyThe current outbreak of HPAI H5N1 virus infections in dairy cattle in the USA underscores the need for easily accessible methods to rapidly assess host susceptibility for infection with known and emerging influenza viruses. Here we show that ex vivo lung slice cultures from calves provide a useful method to rapidly screen host susceptibility to a range of influenza A viruses.https://www.tandfonline.com/doi/10.1080/22221751.2024.2432368InfluenzaHPAI H5N1lung slicescattlespecies susceptibility |
| spellingShingle | Kate Guilfoyle Monica Mirolo Geert van Amerongen Guido van der Net Mara Sophie Lombardo Theresa Störk Guus Rimmelzwaan Martin Ludlow Albert Osterhaus Susceptibility of calf lung slice cultures to H5N1 influenza virus Emerging Microbes and Infections Influenza HPAI H5N1 lung slices cattle species susceptibility |
| title | Susceptibility of calf lung slice cultures to H5N1 influenza virus |
| title_full | Susceptibility of calf lung slice cultures to H5N1 influenza virus |
| title_fullStr | Susceptibility of calf lung slice cultures to H5N1 influenza virus |
| title_full_unstemmed | Susceptibility of calf lung slice cultures to H5N1 influenza virus |
| title_short | Susceptibility of calf lung slice cultures to H5N1 influenza virus |
| title_sort | susceptibility of calf lung slice cultures to h5n1 influenza virus |
| topic | Influenza HPAI H5N1 lung slices cattle species susceptibility |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2024.2432368 |
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