Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study
ObjectivesTo assess treatment and identify predictive factors of worsening in COVID-19 patients.MethodsThis study was ambispective (both prospective and retrospective) and part of a multidisciplinary, multicenter project designed to generate epidemiological, sociological and anthropological data abo...
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Frontiers Media S.A.
2025-07-01
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| author | Ariane Mamguem Kamga Samiratou Ouédraogo Firmin Nongodo Kaboré Isidore Tiandiogo Traoré Esperance Ouédraogo Armel Poda Armel Poda Arnaud Eric Diendéré Dramane Kania Hermann Badolo Guillaume Sanou Amariane Koné Therese Samdapawindé Kagoné Blahima Konaté Rachel Médah Nathalie de Rekeneire Boukary Ouédraogo Oumar Billa Gilles Paradis Halidou Tinto Tienhan Sandrine Dabakuyo-yonli |
| author_facet | Ariane Mamguem Kamga Samiratou Ouédraogo Firmin Nongodo Kaboré Isidore Tiandiogo Traoré Esperance Ouédraogo Armel Poda Armel Poda Arnaud Eric Diendéré Dramane Kania Hermann Badolo Guillaume Sanou Amariane Koné Therese Samdapawindé Kagoné Blahima Konaté Rachel Médah Nathalie de Rekeneire Boukary Ouédraogo Oumar Billa Gilles Paradis Halidou Tinto Tienhan Sandrine Dabakuyo-yonli |
| author_sort | Ariane Mamguem Kamga |
| collection | DOAJ |
| description | ObjectivesTo assess treatment and identify predictive factors of worsening in COVID-19 patients.MethodsThis study was ambispective (both prospective and retrospective) and part of a multidisciplinary, multicenter project designed to generate epidemiological, sociological and anthropological data about the COVID-19 epidemic in Burkina Faso. Medical records of patients admitted for COVID-19 at the hospitals of Ouagadougou and Bobo-Dioulasso from March 2020 to April 2021 were reviewed. To identify predictive factors of severe complications, we used Poisson regression models.ResultsIn total, 1,511 patients were included, of whom 70% were aged ≤50 years, 59% were men and 97% were living in an urban area. Of the 86% of patients treated, 92.9% of them received the combo Azithromycin-hydroxychloroquine. A total of 78 (5.2%) patients experienced complications during hospitalization, and 49 (3.3%) patients died. Multivariate analysis identified patient's age, residence and comorbidity as factors associated with poor outcomes.ConclusionsAlthough most people had symptoms, most of them recovered without sequelae, and few patients had severe forms of disease. Age was a strong predictor of worse outcomes in this population. |
| format | Article |
| id | doaj-art-2b0a5da0a63a447ba7d2477c33935e85 |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj-art-2b0a5da0a63a447ba7d2477c33935e852025-08-20T03:28:47ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-07-011310.3389/fpubh.2025.15420241542024Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective studyAriane Mamguem Kamga0Samiratou Ouédraogo1Firmin Nongodo Kaboré2Isidore Tiandiogo Traoré3Esperance Ouédraogo4Armel Poda5Armel Poda6Arnaud Eric Diendéré7Dramane Kania8Hermann Badolo9Guillaume Sanou10Amariane Koné11Therese Samdapawindé Kagoné12Blahima Konaté13Rachel Médah14Nathalie de Rekeneire15Boukary Ouédraogo16Oumar Billa17Gilles Paradis18Halidou Tinto19Tienhan Sandrine Dabakuyo-yonli20Centre Georges François Leclerc, Dijon, FranceNational Population Health Observatory, National Institute of Public Health, Ouagadougou, Burkina FasoMURAZ Center, Bobo-Dioulasso, Burkina FasoMURAZ Center, Bobo-Dioulasso, Burkina FasoCentre National de la Recherche Scientifique et Technologique, Ouagadougou, Burkina FasoDepartment of Infectious Diseases, Sourô Sanou University Hospital, Bobo Dioulasso, Burkina FasoHigher Institute of Health Sciences, Nazi Boni University, Bobo Dioulasso, Burkina FasoBogodogo University Hospital, Ouagadougou, Burkina FasoMURAZ Center, Bobo-Dioulasso, Burkina FasoNational Population Health Observatory, National Institute of Public Health, Ouagadougou, Burkina FasoNational Population Health Observatory, National Institute of Public Health, Ouagadougou, Burkina FasoMURAZ Center, Bobo-Dioulasso, Burkina FasoMURAZ Center, Bobo-Dioulasso, Burkina FasoCentre National de la Recherche Scientifique et Technologique, Ouagadougou, Burkina FasoMURAZ Center, Bobo-Dioulasso, Burkina FasoExpertise France, Paris, FranceBogodogo University Hospital, Ouagadougou, Burkina FasoCentre Georges François Leclerc, Dijon, FranceMcGill University, Montreal, QA, Canada0Nanoro Clinical Research Unit, Health Sciences Research Institute, National Centre for Scientific and Technological Research, Bobo Dioulasso, Burkina FasoCentre Georges François Leclerc, Dijon, FranceObjectivesTo assess treatment and identify predictive factors of worsening in COVID-19 patients.MethodsThis study was ambispective (both prospective and retrospective) and part of a multidisciplinary, multicenter project designed to generate epidemiological, sociological and anthropological data about the COVID-19 epidemic in Burkina Faso. Medical records of patients admitted for COVID-19 at the hospitals of Ouagadougou and Bobo-Dioulasso from March 2020 to April 2021 were reviewed. To identify predictive factors of severe complications, we used Poisson regression models.ResultsIn total, 1,511 patients were included, of whom 70% were aged ≤50 years, 59% were men and 97% were living in an urban area. Of the 86% of patients treated, 92.9% of them received the combo Azithromycin-hydroxychloroquine. A total of 78 (5.2%) patients experienced complications during hospitalization, and 49 (3.3%) patients died. Multivariate analysis identified patient's age, residence and comorbidity as factors associated with poor outcomes.ConclusionsAlthough most people had symptoms, most of them recovered without sequelae, and few patients had severe forms of disease. Age was a strong predictor of worse outcomes in this population.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1542024/fullagecomorbidityCOVID-19complicationstreatment |
| spellingShingle | Ariane Mamguem Kamga Samiratou Ouédraogo Firmin Nongodo Kaboré Isidore Tiandiogo Traoré Esperance Ouédraogo Armel Poda Armel Poda Arnaud Eric Diendéré Dramane Kania Hermann Badolo Guillaume Sanou Amariane Koné Therese Samdapawindé Kagoné Blahima Konaté Rachel Médah Nathalie de Rekeneire Boukary Ouédraogo Oumar Billa Gilles Paradis Halidou Tinto Tienhan Sandrine Dabakuyo-yonli Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study Frontiers in Public Health age comorbidity COVID-19 complications treatment |
| title | Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study |
| title_full | Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study |
| title_fullStr | Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study |
| title_full_unstemmed | Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study |
| title_short | Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study |
| title_sort | characteristics management and factors associated with poor outcomes in covid 19 patients in burkina faso insights from a 2021 large scale ambispective study |
| topic | age comorbidity COVID-19 complications treatment |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2025.1542024/full |
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