Assessment of pharmacokinetics-pharmacodynamics relationship of tropoxine in rats
ResuLts of precLinicaL pharmacodynamic and pharmacokinetic study of tropoxine (a new originaL antimigraine drug) after singLe intravenous administration in rats were presented. Tropoxine in significant extent suppresses constricting reactions of rat brain vesseLs, serotonin, and agonist of 5НТ2В/2С...
Saved in:
| Main Authors: | V. P. Zherdev, G. B. Kolyvanov, A. A. Litvin, A. A. Novitskyi, T. S. Ganshina, A. A. Gorbunov, R. S. Mirzoyan |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
LLC “Publisher OKI”
2016-09-01
|
| Series: | Фармакокинетика и Фармакодинамика |
| Subjects: | |
| Online Access: | https://www.pharmacokinetica.ru/jour/article/view/179 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Clinical pharmacokinetics of а new original dipeptide anxiolytic GB-115
by: V. P. Zherdev, et al.
Published: (2017-02-01) -
Pharmacokinetic comparative study of tropoxine metabolite in miscellaneous animal species and humans
by: V. P. Zherdev, et al.
Published: (2017-03-01) -
10th anniversary of the journal «Pharmacokinetics and pharmacodynamics»
by: V. P. Zherdev
Published: (2014-04-01) -
Study of acute toxicity of the drug Tropoxin
by: A. V. Sorokina, et al.
Published: (2017-07-01) -
Development and validation of the quantification of GIZH-298, possessing in the rat blood plasma by HPLC-UF
by: O. G. Gribakina, et al.
Published: (2019-02-01)