Involvement of KLF11 in hepatic glucose metabolism in mice via suppressing of PEPCK-C expression.

Involvement of KLF11 in hepatic glucose metabolism in mice via suppressing of PEPCK-C expression.

<h4>Background</h4>Abnormal hepatic gluconeogenesis is related to hyperglycemia in mammals with insulin resistance. Despite the strong evidences linking Krüppel-like factor 11 (KLF11) gene mutations to development of Type 2 diabetes, the precise physiological functions of KLF11 in vivo r...

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Main Authors: Huabing Zhang, Qi Chen, Tao Jiao, Anfang Cui, Xiujing Sun, Weijun Fang, Liwei Xie, Yang Liu, Fude Fang, Yongsheng Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089552&type=printable
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