Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops

ABSTRACT Due to rapid global population growth and the resulting significant increase in food demand, the world is facing an epidemic of malnutrition. Although yield improvement remains one of the main targets of breeding programs, much attention is being paid to the nutritional aspects of crops, in...

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Main Authors: Maria Dellino, Claudio deGiovanni, Monica Marilena Miazzi, Cinzia Montemurro, Domenica Nigro
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Food Frontiers
Subjects:
Online Access:https://doi.org/10.1002/fft2.70005
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author Maria Dellino
Claudio deGiovanni
Monica Marilena Miazzi
Cinzia Montemurro
Domenica Nigro
author_facet Maria Dellino
Claudio deGiovanni
Monica Marilena Miazzi
Cinzia Montemurro
Domenica Nigro
author_sort Maria Dellino
collection DOAJ
description ABSTRACT Due to rapid global population growth and the resulting significant increase in food demand, the world is facing an epidemic of malnutrition. Although yield improvement remains one of the main targets of breeding programs, much attention is being paid to the nutritional aspects of crops, including nutrients and bioactive compounds that are often important for general human health and disease prevention. Phytocompounds such as allergens, antinutrients, antioxidants, vitamins, and fatty acids are among the most important classes of chemical substances that affect human health and thus contribute to the nutritional value of crops. Conventional breeding for these traits consists of laborious and time‐consuming methods, but recent advances in new genome editing (GE) technologies offer a valuable, time‐saving, and cost‐effective alternative. The article reports on the extensive use of GE tools to modify the content of health‐relevant bio‐compounds and to obtain crops with higher nutritional quality.
format Article
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institution Kabale University
issn 2643-8429
language English
publishDate 2025-05-01
publisher Wiley
record_format Article
series Food Frontiers
spelling doaj-art-2af64c51bcde4a8d83f2419f79c06dd32025-08-20T03:48:22ZengWileyFood Frontiers2643-84292025-05-01631271128610.1002/fft2.70005Genome Editing Technologies to Improve Health‐Related Phytocompounds in CropsMaria Dellino0Claudio deGiovanni1Monica Marilena Miazzi2Cinzia Montemurro3Domenica Nigro4Department of Soil, Plant and Food Sciences (DiSSPA) University of Bari Aldo Moro Bari ItalyDepartment of Soil, Plant and Food Sciences (DiSSPA) University of Bari Aldo Moro Bari ItalyDepartment of Soil, Plant and Food Sciences (DiSSPA) University of Bari Aldo Moro Bari ItalyDepartment of Soil, Plant and Food Sciences (DiSSPA) University of Bari Aldo Moro Bari ItalyDepartment of Soil, Plant and Food Sciences (DiSSPA) University of Bari Aldo Moro Bari ItalyABSTRACT Due to rapid global population growth and the resulting significant increase in food demand, the world is facing an epidemic of malnutrition. Although yield improvement remains one of the main targets of breeding programs, much attention is being paid to the nutritional aspects of crops, including nutrients and bioactive compounds that are often important for general human health and disease prevention. Phytocompounds such as allergens, antinutrients, antioxidants, vitamins, and fatty acids are among the most important classes of chemical substances that affect human health and thus contribute to the nutritional value of crops. Conventional breeding for these traits consists of laborious and time‐consuming methods, but recent advances in new genome editing (GE) technologies offer a valuable, time‐saving, and cost‐effective alternative. The article reports on the extensive use of GE tools to modify the content of health‐relevant bio‐compounds and to obtain crops with higher nutritional quality.https://doi.org/10.1002/fft2.70005CRISPR/Cas9crop breedingfoodgenome editingnutritional qualityphytocompounds
spellingShingle Maria Dellino
Claudio deGiovanni
Monica Marilena Miazzi
Cinzia Montemurro
Domenica Nigro
Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops
Food Frontiers
CRISPR/Cas9
crop breeding
food
genome editing
nutritional quality
phytocompounds
title Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops
title_full Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops
title_fullStr Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops
title_full_unstemmed Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops
title_short Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops
title_sort genome editing technologies to improve health related phytocompounds in crops
topic CRISPR/Cas9
crop breeding
food
genome editing
nutritional quality
phytocompounds
url https://doi.org/10.1002/fft2.70005
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AT claudiodegiovanni genomeeditingtechnologiestoimprovehealthrelatedphytocompoundsincrops
AT monicamarilenamiazzi genomeeditingtechnologiestoimprovehealthrelatedphytocompoundsincrops
AT cinziamontemurro genomeeditingtechnologiestoimprovehealthrelatedphytocompoundsincrops
AT domenicanigro genomeeditingtechnologiestoimprovehealthrelatedphytocompoundsincrops