A study protocol for a double-blinded, randomised, placebo-controlled trial on the use of encapsulated FMT for reducing the side effects of HSCT: the HSCT-BIOME study

A study protocol for a double-blinded, randomised, placebo-controlled trial on the use of encapsulated FMT for reducing the side effects of HSCT: the HSCT-BIOME study

Abstract Background The composition of the gut microbiota both prior to and after haematopoietic stem cell transplantation (HSCT) is increasingly implicated in the outcomes of HSCT, including infections, poor immune reconstitution and disease relapse. Faecal microbiota transplantation (FMT) offers a...

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Main Authors: Anna Li, Sam P. Costello, Robert V. Bryant, Sarah Haylock-Jacobs, Craig Haifer, Cindy Lee, David Yeung, Pratyush Giri, Danielle Blunt, Joanne B. Bowen, Feargal J. Ryan, Angelina Yong, Hannah R. Wardill
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Autologous haematopoeitic stem cell transplantation
Capsule fecal microbiota transplantation
Peri-HSCT fecal microbiota transplantation
Online Access:https://doi.org/10.1186/s12885-025-14057-4
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