Dedifferentiated liposarcomas treated with immune checkpoint blockade: the MD Anderson experience

Dedifferentiated liposarcomas treated with immune checkpoint blockade: the MD Anderson experience

BackgroundDedifferentiated liposarcoma (DDLPS) is one of the most common types of soft tissue sarcoma (STS) characterized by liposarcomatous differentiation and a predilection for the retroperitoneum. Despite the growing number of histology-specific immune checkpoint blockade (ICB) trials in STS, it...

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Main Authors: Madeline B. Torres, Cheuk Hong Leung, Marianne Zoghbi, Rossana Lazcano, Davis Ingram, Khalida Wani, Emily Z. Keung, M. Alejandra Zarzour, Christopher P. Scally, Kelly K. Hunt, Anthony Conley, Andrew J. Bishop, B. Ashleigh Guadagnolo, Ahsan Farooqi, Devarati Mitra, Alison K. Yoder, Michael S. Nakazawa, Dejka Araujo, Andrew Livingston, Ravin Ratan, Shreyaskumar Patel, Vinod Ravi, Alexander J. Lazar, Christina L. Roland, Neeta Somaiah, Elise F. Nassif Haddad
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
sarcoma
dedifferentiated liposarcoma
Anti-PD1
immunotherapy
immune-checkpoint inhibitors
survival
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567736/full
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