Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature
Colorectal adenocarcinoma is the second cause of cancer-related deaths in the United States. The occurrence of squamous cell carcinoma in the colorectum is extremely unusual. Malignant transformation from mature cystic teratoma of the ovary is a rare event. The most common transformation is squamous...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2015/905462 |
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| author | Claudia P. Rojas Parvin Ganjei-Azar Monica T. Garcia-Buitrago |
| author_facet | Claudia P. Rojas Parvin Ganjei-Azar Monica T. Garcia-Buitrago |
| author_sort | Claudia P. Rojas |
| collection | DOAJ |
| description | Colorectal adenocarcinoma is the second cause of cancer-related deaths in the United States. The occurrence of squamous cell carcinoma in the colorectum is extremely unusual. Malignant transformation from mature cystic teratoma of the ovary is a rare event. The most common transformation is squamous cell carcinoma, followed by adenocarcinoma. It occurs more often in elderly patients, who usually present with advance disease. We report two unusual cases of postmenopausal women diagnosed with squamous cell carcinoma in colon biopsies. After surgical resections, the carcinoma was proven to be the result of malignant transformation of ovarian mature cystic teratomas. Since squamous cell carcinoma of the colorectum is extremely rare, the presence of squamous cell carcinoma in a colonic biopsy in a female patient should alert the clinicians to other possible primary sites, as seen in these cases. |
| format | Article |
| id | doaj-art-2ae6238440974cdb8193e2b8192e3099 |
| institution | OA Journals |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-2ae6238440974cdb8193e2b8192e30992025-08-20T02:04:10ZengWileyCase Reports in Pathology2090-67812090-679X2015-01-01201510.1155/2015/905462905462Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the LiteratureClaudia P. Rojas0Parvin Ganjei-Azar1Monica T. Garcia-Buitrago2Department of Pathology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, 1611 NW 12th Avenue, Holtz 2042C, Miami, FL 33136, USADepartment of Pathology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, 1611 NW 12th Avenue, Holtz 2042C, Miami, FL 33136, USADepartment of Pathology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, 1611 NW 12th Avenue, Holtz 2042C, Miami, FL 33136, USAColorectal adenocarcinoma is the second cause of cancer-related deaths in the United States. The occurrence of squamous cell carcinoma in the colorectum is extremely unusual. Malignant transformation from mature cystic teratoma of the ovary is a rare event. The most common transformation is squamous cell carcinoma, followed by adenocarcinoma. It occurs more often in elderly patients, who usually present with advance disease. We report two unusual cases of postmenopausal women diagnosed with squamous cell carcinoma in colon biopsies. After surgical resections, the carcinoma was proven to be the result of malignant transformation of ovarian mature cystic teratomas. Since squamous cell carcinoma of the colorectum is extremely rare, the presence of squamous cell carcinoma in a colonic biopsy in a female patient should alert the clinicians to other possible primary sites, as seen in these cases.http://dx.doi.org/10.1155/2015/905462 |
| spellingShingle | Claudia P. Rojas Parvin Ganjei-Azar Monica T. Garcia-Buitrago Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature Case Reports in Pathology |
| title | Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature |
| title_full | Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature |
| title_fullStr | Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature |
| title_full_unstemmed | Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature |
| title_short | Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature |
| title_sort | unexpected malignant diagnosis in colonic biopsies malignant transformation of ovarian mature teratomas two case reports and review of the literature |
| url | http://dx.doi.org/10.1155/2015/905462 |
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