The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure
Background. Recurrent glottic squamous cell carcinomas following radiation therapy for early staged tumors are oftentime early staged tumors. Management of these early stage recurrences presents a dilemma for the head and neck surgeon. Difficulties in appropriate tumor mapping, preoperative analysis...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2016/2706463 |
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| _version_ | 1832549494089056256 |
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| author | Moustafa Mourad Sami P. Moubayed Ilya Likhterov Mark Urken |
| author_facet | Moustafa Mourad Sami P. Moubayed Ilya Likhterov Mark Urken |
| author_sort | Moustafa Mourad |
| collection | DOAJ |
| description | Background. Recurrent glottic squamous cell carcinomas following radiation therapy for early staged tumors are oftentime early staged tumors. Management of these early stage recurrences presents a dilemma for the head and neck surgeon. Difficulties in appropriate tumor mapping, preoperative analysis, and poor understanding of the virulent pathologic nature of the recurrence may impede surgical decision-making. Methods. This is a single surgeon case report, presenting a patient with rapid recurrence following salvage transoral resection for an early stage recurrence, necessitating a total laryngectomy. Results. A review of the literature was performed, identifying studies that expound on the pathologic behavior of radiation recurrent disease. Conclusions. Radiation recurrent glottic squamous cell carcinoma has a distinct pathologic behavior and aggressive nature. Disease virulence, coupled with difficulty in appropriate staging and preoperative tumor mapping, should guide the surgeon when deciding the surgical management in the salvage setting. |
| format | Article |
| id | doaj-art-2ae3d167bda84d50b032ed1877bd879e |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-2ae3d167bda84d50b032ed1877bd879e2025-02-03T06:11:12ZengWileyCase Reports in Otolaryngology2090-67652090-67732016-01-01201610.1155/2016/27064632706463The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation FailureMoustafa Mourad0Sami P. Moubayed1Ilya Likhterov2Mark Urken3Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY 10003, USADepartment of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY 10003, USADepartment of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY 10003, USADepartment of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY 10003, USABackground. Recurrent glottic squamous cell carcinomas following radiation therapy for early staged tumors are oftentime early staged tumors. Management of these early stage recurrences presents a dilemma for the head and neck surgeon. Difficulties in appropriate tumor mapping, preoperative analysis, and poor understanding of the virulent pathologic nature of the recurrence may impede surgical decision-making. Methods. This is a single surgeon case report, presenting a patient with rapid recurrence following salvage transoral resection for an early stage recurrence, necessitating a total laryngectomy. Results. A review of the literature was performed, identifying studies that expound on the pathologic behavior of radiation recurrent disease. Conclusions. Radiation recurrent glottic squamous cell carcinoma has a distinct pathologic behavior and aggressive nature. Disease virulence, coupled with difficulty in appropriate staging and preoperative tumor mapping, should guide the surgeon when deciding the surgical management in the salvage setting.http://dx.doi.org/10.1155/2016/2706463 |
| spellingShingle | Moustafa Mourad Sami P. Moubayed Ilya Likhterov Mark Urken The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure Case Reports in Otolaryngology |
| title | The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure |
| title_full | The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure |
| title_fullStr | The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure |
| title_full_unstemmed | The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure |
| title_short | The Clinical Understaging of Recurrent Glottic Carcinoma after Radiation Failure |
| title_sort | clinical understaging of recurrent glottic carcinoma after radiation failure |
| url | http://dx.doi.org/10.1155/2016/2706463 |
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