Absolute Quantification of Choline-Related Biomarkers in Breast Cancer Biopsies by Liquid Chromatography Electrospray Ionization Mass Spectrometry

Absolute Quantification of Choline-Related Biomarkers in Breast Cancer Biopsies by Liquid Chromatography Electrospray Ionization Mass Spectrometry

It has been repeatedly demonstrated that choline metabolism is altered in a wide variety of cancers. In breast tumours, the choline metabolite profile is characterized by an elevation of phosphocholine and total choline-compounds. This pattern is increasingly being exploited as biomarker in cancer d...

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Bibliographic Details
Main Authors: Maria Chiara Mimmi, Nicoletta Finato, Gloria Pizzolato, Carlo Alberto Beltrami, Federico Fogolari, Alessandra Corazza, Gennaro Esposito
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.3233/ACP-130082
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