Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization
Conclusion: These findings may provide new insights into the role of orphan class A GPR genes in STAD and identify GPR176 as a new therapeutic target for GC.
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/mi/7977933 |
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| _version_ | 1849316775122960384 |
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| author | Jiahui Lin Lingling Ke Sha Cheng Wei Lu Yanan Hu Xiyi He Tingting Luo Yuting Liu Canxia Xu Jian Qi |
| author_facet | Jiahui Lin Lingling Ke Sha Cheng Wei Lu Yanan Hu Xiyi He Tingting Luo Yuting Liu Canxia Xu Jian Qi |
| author_sort | Jiahui Lin |
| collection | DOAJ |
| description | Conclusion: These findings may provide new insights into the role of orphan class A GPR genes in STAD and identify GPR176 as a new therapeutic target for GC. |
| format | Article |
| id | doaj-art-2ad86b31fecb4094914578bc1339fb22 |
| institution | Kabale University |
| issn | 1466-1861 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-2ad86b31fecb4094914578bc1339fb222025-08-20T03:51:29ZengWileyMediators of Inflammation1466-18612025-01-01202510.1155/mi/7977933Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage PolarizationJiahui Lin0Lingling Ke1Sha Cheng2Wei Lu3Yanan Hu4Xiyi He5Tingting Luo6Yuting Liu7Canxia Xu8Jian Qi9Digestive Diseases CenterDigestive Diseases CenterDepartment of GastroenterologyDepartment of GastroenterologyDepartment of Pediatric Pulmonology and ImmunologyDepartment of Laboratory MedicineDigestive Diseases CenterDigestive Diseases CenterDepartment of GastroenterologyDigestive Diseases CenterConclusion: These findings may provide new insights into the role of orphan class A GPR genes in STAD and identify GPR176 as a new therapeutic target for GC.http://dx.doi.org/10.1155/mi/7977933 |
| spellingShingle | Jiahui Lin Lingling Ke Sha Cheng Wei Lu Yanan Hu Xiyi He Tingting Luo Yuting Liu Canxia Xu Jian Qi Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization Mediators of Inflammation |
| title | Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization |
| title_full | Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization |
| title_fullStr | Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization |
| title_full_unstemmed | Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization |
| title_short | Orphan Class A GPCRs Signature Predicts Prognosis and Immune Microenvironment in Gastric Cancer: GPR176 Drives Tumor Progression Through Wnt Signaling and Macrophage Polarization |
| title_sort | orphan class a gpcrs signature predicts prognosis and immune microenvironment in gastric cancer gpr176 drives tumor progression through wnt signaling and macrophage polarization |
| url | http://dx.doi.org/10.1155/mi/7977933 |
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