Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

The mammalian suprachiasmatic nucleus (SCN), situated in the ventral hypothalamus, directs daily cellular and physiological rhythms across the body. The SCN clockwork is a self-sustaining transcriptional-translational feedback loop (TTFL) that in turn coordinates the expression of clock-controlled g...

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Bibliographic Details
Main Authors: Akanksha Bafna, Gareth Banks, Vadim Vasilyev, Robert Dallmann, Michael H Hastings, Patrick M Nolan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-03-01
Series:eLife
Subjects:
circadian rhythm
genomics
SCN
Online Access:https://elifesciences.org/articles/102019
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