Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of Prematurity
Purpose. To examine the macular findings obtained with spectral domain optical coherence tomography (SD OCT) in infants with retinopathy of prematurity (ROP). Materials and Methods. The macular SD OCT images of 190 premature infants were analyzed. Data regarding central foveal thickness (CFT), cysto...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/468653 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832551866921123840 |
|---|---|
| author | Muhammet Kazim Erol Ozdemir Ozdemir Deniz Turgut Coban Ahmet Burak Bilgin Berna Dogan Esin Sogutlu Sari Devrim Toslak |
| author_facet | Muhammet Kazim Erol Ozdemir Ozdemir Deniz Turgut Coban Ahmet Burak Bilgin Berna Dogan Esin Sogutlu Sari Devrim Toslak |
| author_sort | Muhammet Kazim Erol |
| collection | DOAJ |
| description | Purpose. To examine the macular findings obtained with spectral domain optical coherence tomography (SD OCT) in infants with retinopathy of prematurity (ROP). Materials and Methods. The macular SD OCT images of 190 premature infants were analyzed. Data regarding central foveal thickness (CFT), cystoid macular edema (CME), and cyst grading were compared. The relationships of CFT with gestational age and birth weight were investigated. Results. The results were obtained from 358 eyes of 179 infants (81 females and 98 males) of a mean gestational age of 30.9±2.7 weeks and a mean birth weight of 1609±477 g. ROP was diagnosed in 126 eyes and CME in 139 eyes. A significantly greater percentage of eyes with ROP were found to have CME (54%) compared to eyes without ROP (31%; P=0.001). The incidence of CME was 46.3% for stage 1 ROP, 57.1% for stage 2, and 87.5% for stage 3. There was a weakly inverse correlation between CFT, gestational age, and birth weight (P=0.025, r=-0.227; P=0.002, r=-0.182, resp., Spearman correlation test). Conclusions. High-quality SD OCT images can be obtained from premature infants using the iVue system. Severity and frequency of CME in premature infants increase as stage of ROP increases. |
| format | Article |
| id | doaj-art-2ad38c2bbb994f59b48f6d2e88127902 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-2ad38c2bbb994f59b48f6d2e881279022025-02-03T06:00:16ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/468653468653Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of PrematurityMuhammet Kazim Erol0Ozdemir Ozdemir1Deniz Turgut Coban2Ahmet Burak Bilgin3Berna Dogan4Esin Sogutlu Sari5Devrim Toslak6Department of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, TurkeyDepartment of Ophthalmology, Zekai Tahir Burak Women’s Health Training and Research Hospital, 06110 Ankara, TurkeyDepartment of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, TurkeyDepartment of Ophthalmology, Faculty of Medicine, Akdeniz University, 07070 Antalya, TurkeyDepartment of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, TurkeyDepartment of Ophthalmology, Faculty of Medicine, Balıkesir University, 10145 Balıkesir, TurkeyDepartment of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, TurkeyPurpose. To examine the macular findings obtained with spectral domain optical coherence tomography (SD OCT) in infants with retinopathy of prematurity (ROP). Materials and Methods. The macular SD OCT images of 190 premature infants were analyzed. Data regarding central foveal thickness (CFT), cystoid macular edema (CME), and cyst grading were compared. The relationships of CFT with gestational age and birth weight were investigated. Results. The results were obtained from 358 eyes of 179 infants (81 females and 98 males) of a mean gestational age of 30.9±2.7 weeks and a mean birth weight of 1609±477 g. ROP was diagnosed in 126 eyes and CME in 139 eyes. A significantly greater percentage of eyes with ROP were found to have CME (54%) compared to eyes without ROP (31%; P=0.001). The incidence of CME was 46.3% for stage 1 ROP, 57.1% for stage 2, and 87.5% for stage 3. There was a weakly inverse correlation between CFT, gestational age, and birth weight (P=0.025, r=-0.227; P=0.002, r=-0.182, resp., Spearman correlation test). Conclusions. High-quality SD OCT images can be obtained from premature infants using the iVue system. Severity and frequency of CME in premature infants increase as stage of ROP increases.http://dx.doi.org/10.1155/2014/468653 |
| spellingShingle | Muhammet Kazim Erol Ozdemir Ozdemir Deniz Turgut Coban Ahmet Burak Bilgin Berna Dogan Esin Sogutlu Sari Devrim Toslak Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of Prematurity Journal of Ophthalmology |
| title | Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of Prematurity |
| title_full | Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of Prematurity |
| title_fullStr | Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of Prematurity |
| title_full_unstemmed | Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of Prematurity |
| title_short | Macular Findings Obtained by Spectral Domain Optical Coherence Tomography in Retinopathy of Prematurity |
| title_sort | macular findings obtained by spectral domain optical coherence tomography in retinopathy of prematurity |
| url | http://dx.doi.org/10.1155/2014/468653 |
| work_keys_str_mv | AT muhammetkazimerol macularfindingsobtainedbyspectraldomainopticalcoherencetomographyinretinopathyofprematurity AT ozdemirozdemir macularfindingsobtainedbyspectraldomainopticalcoherencetomographyinretinopathyofprematurity AT denizturgutcoban macularfindingsobtainedbyspectraldomainopticalcoherencetomographyinretinopathyofprematurity AT ahmetburakbilgin macularfindingsobtainedbyspectraldomainopticalcoherencetomographyinretinopathyofprematurity AT bernadogan macularfindingsobtainedbyspectraldomainopticalcoherencetomographyinretinopathyofprematurity AT esinsogutlusari macularfindingsobtainedbyspectraldomainopticalcoherencetomographyinretinopathyofprematurity AT devrimtoslak macularfindingsobtainedbyspectraldomainopticalcoherencetomographyinretinopathyofprematurity |