Advancements in complement inhibition for PNH and primary complement–mediated thrombotic microangiopathy
Abstract: Paroxysmal nocturnal hemoglobinuria (PNH) and primary complement–mediated thrombotic microangiopathy, also known as atypical hemolytic uremic syndrome (aHUS), are hematologic disorders characterized by dysregulation of the complement system leading to hemolysis and other systemic and poten...
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| Main Authors: | Thalia Padilla Kelley, Hannah King, Aditya Malhotra, Thomas G. DeLoughery, Kylee Martens, Joseph J. Shatzel |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | Blood Advances |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2473952925002873 |
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