Modern conceptions of serological tumor markers and their role in oncology

The paper reviews modern concepts of serological tumor markers and their place in oncology: using for differential diagnostics, in the prognosis of the tumor, follow-up and for preclinical revealing of relapses, as well as in the screening aimed at early detection of malignant neoplasms. Biochemical...

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Main Authors: N. S. Sergeeva, N. V. Marshutina, M. P. Solokhina, I. I. Alentov, N. K. Parilova, E. V. Zenkina, T. E. Skashchkova
Format: Article
Language:Russian
Published: ABV-press 2015-06-01
Series:Успехи молекулярной онкологии
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Online Access:https://umo.abvpress.ru/jour/article/view/18
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author N. S. Sergeeva
N. V. Marshutina
M. P. Solokhina
I. I. Alentov
N. K. Parilova
E. V. Zenkina
T. E. Skashchkova
author_facet N. S. Sergeeva
N. V. Marshutina
M. P. Solokhina
I. I. Alentov
N. K. Parilova
E. V. Zenkina
T. E. Skashchkova
author_sort N. S. Sergeeva
collection DOAJ
description The paper reviews modern concepts of serological tumor markers and their place in oncology: using for differential diagnostics, in the prognosis of the tumor, follow-up and for preclinical revealing of relapses, as well as in the screening aimed at early detection of malignant neoplasms. Biochemical characteristics and functions of most informative tumor markers (CA125, PSA etc.) were described. Currently diagnostic indexes, obtained by the in vitro diagnostic multivariate index assay (IVDMIA), and algorithms using several serological markers begin to apply in laboratory practice to increase diagnostic accuracy. Also some promising new serological tumor markers were described in this review.
format Article
id doaj-art-2ac8d26de08d43958a76c880302bfac4
institution DOAJ
issn 2313-805X
2413-3787
language Russian
publishDate 2015-06-01
publisher ABV-press
record_format Article
series Успехи молекулярной онкологии
spelling doaj-art-2ac8d26de08d43958a76c880302bfac42025-08-20T03:00:58ZrusABV-pressУспехи молекулярной онкологии2313-805X2413-37872015-06-0111698010.17650/2313-805X.2014.1.1.69-8018Modern conceptions of serological tumor markers and their role in oncologyN. S. Sergeeva0N. V. Marshutina1M. P. Solokhina2I. I. Alentov3N. K. Parilova4E. V. Zenkina5T. E. Skashchkova6P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of RussiaP.A. Herzen Moscow Oncology Research Institute, Ministry of Health of RussiaP.A. Herzen Moscow Oncology Research Institute, Ministry of Health of RussiaP.A. Herzen Moscow Oncology Research Institute, Ministry of Health of RussiaP.A. Herzen Moscow Oncology Research Institute, Ministry of Health of RussiaP.A. Herzen Moscow Oncology Research Institute, Ministry of Health of RussiaN.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, MoscowThe paper reviews modern concepts of serological tumor markers and their place in oncology: using for differential diagnostics, in the prognosis of the tumor, follow-up and for preclinical revealing of relapses, as well as in the screening aimed at early detection of malignant neoplasms. Biochemical characteristics and functions of most informative tumor markers (CA125, PSA etc.) were described. Currently diagnostic indexes, obtained by the in vitro diagnostic multivariate index assay (IVDMIA), and algorithms using several serological markers begin to apply in laboratory practice to increase diagnostic accuracy. Also some promising new serological tumor markers were described in this review.https://umo.abvpress.ru/jour/article/view/18serological tumor markersmonitoringscreeningca125he4psas100scc
spellingShingle N. S. Sergeeva
N. V. Marshutina
M. P. Solokhina
I. I. Alentov
N. K. Parilova
E. V. Zenkina
T. E. Skashchkova
Modern conceptions of serological tumor markers and their role in oncology
Успехи молекулярной онкологии
serological tumor markers
monitoring
screening
ca125
he4
psa
s100
scc
title Modern conceptions of serological tumor markers and their role in oncology
title_full Modern conceptions of serological tumor markers and their role in oncology
title_fullStr Modern conceptions of serological tumor markers and their role in oncology
title_full_unstemmed Modern conceptions of serological tumor markers and their role in oncology
title_short Modern conceptions of serological tumor markers and their role in oncology
title_sort modern conceptions of serological tumor markers and their role in oncology
topic serological tumor markers
monitoring
screening
ca125
he4
psa
s100
scc
url https://umo.abvpress.ru/jour/article/view/18
work_keys_str_mv AT nssergeeva modernconceptionsofserologicaltumormarkersandtheirroleinoncology
AT nvmarshutina modernconceptionsofserologicaltumormarkersandtheirroleinoncology
AT mpsolokhina modernconceptionsofserologicaltumormarkersandtheirroleinoncology
AT iialentov modernconceptionsofserologicaltumormarkersandtheirroleinoncology
AT nkparilova modernconceptionsofserologicaltumormarkersandtheirroleinoncology
AT evzenkina modernconceptionsofserologicaltumormarkersandtheirroleinoncology
AT teskashchkova modernconceptionsofserologicaltumormarkersandtheirroleinoncology