JAK-STAT pathway, type I/II cytokines, and new potential therapeutic strategy for autoimmune bullous diseases: update on pemphigus vulgaris and bullous pemphigoid

JAK-STAT pathway, type I/II cytokines, and new potential therapeutic strategy for autoimmune bullous diseases: update on pemphigus vulgaris and bullous pemphigoid

Autoimmune Bullous Diseases (AIBDs), characterized by the formation of blisters due to autoantibodies targeting structural proteins, pose significant therapeutic challenges. Current treatments, often involving glucocorticoids or traditional immunosuppressants, are limited by their non-specificity an...

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Bibliographic Details
Main Authors: Xiaoying Lin, Xiang Li, Zhifang Zhai, Mingwang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
autoimmune bullous diseases
pemphigus vulgaris
bullous pemphigoid
JAK inhibitors
cytokines
JAK-STAT pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1563286/full
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