Overall in vitro, in vivo, and in silico evaluation of Olea europaea and Ficus carica leaf extracts for antimicrobial activity against multidrug-resistant pathogens

Overall in vitro, in vivo, and in silico evaluation of Olea europaea and Ficus carica leaf extracts for antimicrobial activity against multidrug-resistant pathogens

IntroductionAntimicrobial resistance (AMR) represents a critical global health issue, prompting the urgent exploration of alternative plant-derived antimicrobial therapies. In this context, the present study evaluates the therapeutic efficacy and safety profiles of Olea europaea and Ficus carica lea...

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Main Authors: Mahmoud Aloriby, Mohamed Elkawafi, Salem Aldrsy, Mohamed Sweker, Hadeel Elabdeli, Aisha Elbarghathi, Ahmed Benhasouna, Madiha El-Awamie, Nariman Elsharif, Omar Alqabbasi, Salmin Alshalmani, Rabiea Algazal, Farag Bleiblo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Microbiology
Subjects:
Olea europae
Ficus carica
multidrug-resistant pathogens
solvent extraction
antimicrobial activities
toxicological evaluation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1567921/full
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