Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid Cancer
Thyroid cancer is one of the fastest growing malignancies in recent years, with an increase of 14.51% per year. It has been shown that there is an association between some biomarkers and the progression of thyroid cancer. In this study, we aim to assess the Neutrophil to Lymphocyte Ratio (NLR) leve...
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middle technical university
2022-11-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/780 |
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| author | Fatima Falah Hassan Wafaa Fadhil Hamed Luma Yousif Mehdi |
| author_facet | Fatima Falah Hassan Wafaa Fadhil Hamed Luma Yousif Mehdi |
| author_sort | Fatima Falah Hassan |
| collection | DOAJ |
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Thyroid cancer is one of the fastest growing malignancies in recent years, with an increase of 14.51% per year. It has been shown that there is an association between some biomarkers and the progression of thyroid cancer. In this study, we aim to assess the Neutrophil to Lymphocyte Ratio (NLR) levels and Thyroid function test (TSH, T3, T4) in patients with thyroid cancer. In the current study, (145) participants were divided into 3 groups: G1: (60 malignant thyroid gland patients, G2: (35 benign thyroid gland patients), and G3: (50 healthy control individuals as a control group). The patients attended to AL-Amal oncology Hospital in Baghdad and Imam Sadiq Hospital in Babylon province, Iraq during the period from November 2021 to February 2022. Depending on hematology analyzer the level of NLR and by Mini Vida's the TSH, T3, T4 were estimated in the studied groups. The results showed that the highest number and percentage of malignant thyroid tumors 21 (35%) was among the age group (50-≥ 60) years, while the lowest number and percentage of malignant tumors 10 (16.7%) was among the age groups (20-29) and (30-39) years. The results also demonstrated that the number and percentage of female patients with malignant thyroid tumors was 43 (71.7%) and males 17 (28.3%). A highly significant increase (P<0.01) in the levels of both NLR and TSH was observed in patients with malignant thyroid cancer when compared with their levels in the control group and benign tumor groups. The current study revealed that the age group (50-≥ 60) years and female patients were most affected by thyroid cancer and both NLR and TSH levels were highly increased in thyroid cancer patients. when compared with healthy group.
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| format | Article |
| id | doaj-art-2abdccab51bd4783a468fa03a215ffa8 |
| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2022-11-01 |
| publisher | middle technical university |
| record_format | Article |
| series | Journal of Techniques |
| spelling | doaj-art-2abdccab51bd4783a468fa03a215ffa82025-01-19T11:07:05Zengmiddle technical universityJournal of Techniques1818-653X2708-83832022-11-014Special Issue10.51173/jt.v4i33.780Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid CancerFatima Falah Hassan0Wafaa Fadhil Hamed1Luma Yousif Mehdi2College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, Iraq Thyroid cancer is one of the fastest growing malignancies in recent years, with an increase of 14.51% per year. It has been shown that there is an association between some biomarkers and the progression of thyroid cancer. In this study, we aim to assess the Neutrophil to Lymphocyte Ratio (NLR) levels and Thyroid function test (TSH, T3, T4) in patients with thyroid cancer. In the current study, (145) participants were divided into 3 groups: G1: (60 malignant thyroid gland patients, G2: (35 benign thyroid gland patients), and G3: (50 healthy control individuals as a control group). The patients attended to AL-Amal oncology Hospital in Baghdad and Imam Sadiq Hospital in Babylon province, Iraq during the period from November 2021 to February 2022. Depending on hematology analyzer the level of NLR and by Mini Vida's the TSH, T3, T4 were estimated in the studied groups. The results showed that the highest number and percentage of malignant thyroid tumors 21 (35%) was among the age group (50-≥ 60) years, while the lowest number and percentage of malignant tumors 10 (16.7%) was among the age groups (20-29) and (30-39) years. The results also demonstrated that the number and percentage of female patients with malignant thyroid tumors was 43 (71.7%) and males 17 (28.3%). A highly significant increase (P<0.01) in the levels of both NLR and TSH was observed in patients with malignant thyroid cancer when compared with their levels in the control group and benign tumor groups. The current study revealed that the age group (50-≥ 60) years and female patients were most affected by thyroid cancer and both NLR and TSH levels were highly increased in thyroid cancer patients. when compared with healthy group. https://journal.mtu.edu.iq/index.php/MTU/article/view/780Malignant & benignThyroid glandT3T4TSHNeutrophil–lymphocyte ratio |
| spellingShingle | Fatima Falah Hassan Wafaa Fadhil Hamed Luma Yousif Mehdi Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid Cancer Journal of Techniques Malignant & benign Thyroid gland T3 T4 TSH Neutrophil–lymphocyte ratio |
| title | Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid Cancer |
| title_full | Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid Cancer |
| title_fullStr | Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid Cancer |
| title_full_unstemmed | Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid Cancer |
| title_short | Neutrophil to Lymphocyte Ratio as a Predictive Factor in Iraqi Patients with Thyroid Cancer |
| title_sort | neutrophil to lymphocyte ratio as a predictive factor in iraqi patients with thyroid cancer |
| topic | Malignant & benign Thyroid gland T3 T4 TSH Neutrophil–lymphocyte ratio |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/780 |
| work_keys_str_mv | AT fatimafalahhassan neutrophiltolymphocyteratioasapredictivefactoriniraqipatientswiththyroidcancer AT wafaafadhilhamed neutrophiltolymphocyteratioasapredictivefactoriniraqipatientswiththyroidcancer AT lumayousifmehdi neutrophiltolymphocyteratioasapredictivefactoriniraqipatientswiththyroidcancer |