Metabolic dysregulation and resistance to high-fat diet-induced weight gain in mice overexpressing human wild-type α-synuclein
Abstract Unintentional weight loss is common among patients with Parkinson’s disease (PD) and is associated with poor quality of life and accelerated disease progression. To explore how early α-synuclein pathology contributes to metabolic dysregulation leading to weight loss in PD, transgenic mice o...
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| Main Authors: | K. C. Biju, Enrique Torres Hernandez, Alison Michelle Stallings, Ada C. Felix-Ortiz, Skanda K. Hebbale, Luke Norton, Michael J. Mader, Robert A. Clark |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | npj Parkinson's Disease |
| Online Access: | https://doi.org/10.1038/s41531-025-00961-w |
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