Plasma testosterone concentration is correlated with circulating immune cell abundance in transgender young people on gender-affirming hormone treatment

Plasma testosterone concentration is correlated with circulating immune cell abundance in transgender young people on gender-affirming hormone treatment

Sex hormones, such as oestrogen and testosterone, display significant immune modulatory properties. This is highly relevant for transgender (trans) people who undergo gender-affirming hormone (GAH) treatment. However, only a limited number of studies have evaluated the immunological impact of GAH tr...

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Bibliographic Details
Main Authors: Alice A. White, Thomas Pearce, Isabelle Coenen, Xander Bickendorf, Julia K. Moore, Penelope Strauss, Liz A. Saunders, Georgia Chaplyn, Aris Siafarikas, Ashleigh Lin, Martyn French, Christian Tjiam, Deborah Strickland, Jonatan Leffler
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
flow cytometry
CyTOF
transgender
B cells
T cells
oestrogen
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608543/full
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