Correlation between P-glycoprotein and CD34 Expressions in Leukemic Cells from De novo Acute Myeloid Leukemia

Correlation between P-glycoprotein and CD34 Expressions in Leukemic Cells from De novo Acute Myeloid Leukemia

Introduction: Acute myeloid leukemia (AML) is a clonal cancer that develops from myeloid progenitors. P-glycoprotein (Pgp) is the membrane transporter encoded by the multidrug resistance (MDR1) gene, which is responsible for the efflux of several chemotherapeutic drugs for the treatment of AML. Pgp’...

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Bibliographic Details
Main Authors: Yulia Nadar Indrasari, Yetti Hernaningsih, Aryati Aryati, Siprianus Ugroseno Yudho Bintoro, Atika Atika, Rosline Hassan
Format: Article
Language:English
Published: Wolters Kluwer – Medknow Publications 2024-12-01
Series:Biomolecular and Health Science Journal
Subjects:
cancer
cd34
de novo acute myeloid leukemia
p-glycoprotein
Online Access:https://journals.lww.com/10.4103/bhsj.bhsj_54_23
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