Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda.

Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda.

<h4>Background</h4>Individuals genetically susceptible to high schistosomiasis worm burden may contribute disproportionately to transmission and could be prioritized for control. Identifying genes involved may guide development of therapy.<h4>Methodology/principal findings</h4&g...

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Main Authors: Oscar Asanya Nyangiri, Julius Mulindwa, Joyce Namulondo, Anna Kitibwa, Jacent Nassuuna, Alison Elliott, Magambo Phillip Kimuda, Alex Boobo, Barbara Nerima, Moses Adriko, Nathan J Dunton, Gaganjit Kaur Madhan, Mark Kristiansen, Miriam Casacuberta-Partal, Harry Noyes, Enock Matovu, TrypanoGEN+ Research group of the H3Africa consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011796&type=printable
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