Rectal prolapse as an initial presentation of colorectal cancer: a systematic review
Abstract Background Colorectal cancer rising incidence still pose a public health challenge. In the present systematic review, we aimed to study the colorectal cancer patients with initial presentation of rectal prolapse. Method The study protocol was developed (PROSPERO CRD42017060473). We searched...
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| Format: | Article |
| Language: | English |
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BMC
2025-03-01
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| Series: | BMC Cancer |
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| Online Access: | https://doi.org/10.1186/s12885-025-13924-4 |
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| author | Fatemeh Shahabi Abbas Abdollahi Mahdieh Zarif-Sadeghian Dorin Ziyaie Ehsan Rahimpour Majid Ansari Esmat Davoudi-Monfared |
| author_facet | Fatemeh Shahabi Abbas Abdollahi Mahdieh Zarif-Sadeghian Dorin Ziyaie Ehsan Rahimpour Majid Ansari Esmat Davoudi-Monfared |
| author_sort | Fatemeh Shahabi |
| collection | DOAJ |
| description | Abstract Background Colorectal cancer rising incidence still pose a public health challenge. In the present systematic review, we aimed to study the colorectal cancer patients with initial presentation of rectal prolapse. Method The study protocol was developed (PROSPERO CRD42017060473). We searched Web of Science, PubMed and Scopus to identify case reports of rectal Prolapse as a chief compliant of colorectal cancer. The Preferred Reporting Items for Systematic Reviews and Meta- Analysis (PRISMA) guidelines were used for screening and data extraction. Results Thirty-one case reports were included in this review. More than half of the patients were females over 65 years old and mean ± SD age of the cases were 64 ± 17.9 years and, the female gender were mentioned in 17 (56%) case reports. The majority (64.5%) of the identified cancer belong to rectum and recto-sigmoid origin's location. In the history retained from the cases, rectal bleeding and constipation were the most frequent reported accompanied symptoms in colorectal cancer cases with initial presentation of rectal prolapse. 67.7% of all identified cases in this review published at 2015 and later. Conclusion Rectal prolapse can be an initial presentation of colorectal cancer, which is more prevalent in female more than 65 years old. The most common symptoms accompanied rectal prolapse were rectal bleeding and constipation. According to rising published case reports on colorectal cancer patients with initial presentation of rectal prolapse in recent years, further work-up is recommended for patients without predisposing factors for a concomitant tumor. |
| format | Article |
| id | doaj-art-2ab4ae80cfab4bfa8bcf16adb551a3ac |
| institution | Kabale University |
| issn | 1471-2407 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj-art-2ab4ae80cfab4bfa8bcf16adb551a3ac2025-08-20T03:41:14ZengBMCBMC Cancer1471-24072025-03-012511910.1186/s12885-025-13924-4Rectal prolapse as an initial presentation of colorectal cancer: a systematic reviewFatemeh Shahabi0Abbas Abdollahi1Mahdieh Zarif-Sadeghian2Dorin Ziyaie3Ehsan Rahimpour4Majid Ansari5Esmat Davoudi-Monfared6Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical SciencesEndoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical SciencesEndoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical SciencesDepartment of Surgery, Ninewells Hospital and Medical SchoolPlastic, Reconstruction and Aesthetic surgery fellow, Department of surgery, School of Medicine, Sina Hospital, Tehran University of medical sciencesEndoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical SciencesHealth Management Research Center, Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical SciencesAbstract Background Colorectal cancer rising incidence still pose a public health challenge. In the present systematic review, we aimed to study the colorectal cancer patients with initial presentation of rectal prolapse. Method The study protocol was developed (PROSPERO CRD42017060473). We searched Web of Science, PubMed and Scopus to identify case reports of rectal Prolapse as a chief compliant of colorectal cancer. The Preferred Reporting Items for Systematic Reviews and Meta- Analysis (PRISMA) guidelines were used for screening and data extraction. Results Thirty-one case reports were included in this review. More than half of the patients were females over 65 years old and mean ± SD age of the cases were 64 ± 17.9 years and, the female gender were mentioned in 17 (56%) case reports. The majority (64.5%) of the identified cancer belong to rectum and recto-sigmoid origin's location. In the history retained from the cases, rectal bleeding and constipation were the most frequent reported accompanied symptoms in colorectal cancer cases with initial presentation of rectal prolapse. 67.7% of all identified cases in this review published at 2015 and later. Conclusion Rectal prolapse can be an initial presentation of colorectal cancer, which is more prevalent in female more than 65 years old. The most common symptoms accompanied rectal prolapse were rectal bleeding and constipation. According to rising published case reports on colorectal cancer patients with initial presentation of rectal prolapse in recent years, further work-up is recommended for patients without predisposing factors for a concomitant tumor.https://doi.org/10.1186/s12885-025-13924-4Rectal prolapseColorectal cancerInitial presentationSystematic review |
| spellingShingle | Fatemeh Shahabi Abbas Abdollahi Mahdieh Zarif-Sadeghian Dorin Ziyaie Ehsan Rahimpour Majid Ansari Esmat Davoudi-Monfared Rectal prolapse as an initial presentation of colorectal cancer: a systematic review BMC Cancer Rectal prolapse Colorectal cancer Initial presentation Systematic review |
| title | Rectal prolapse as an initial presentation of colorectal cancer: a systematic review |
| title_full | Rectal prolapse as an initial presentation of colorectal cancer: a systematic review |
| title_fullStr | Rectal prolapse as an initial presentation of colorectal cancer: a systematic review |
| title_full_unstemmed | Rectal prolapse as an initial presentation of colorectal cancer: a systematic review |
| title_short | Rectal prolapse as an initial presentation of colorectal cancer: a systematic review |
| title_sort | rectal prolapse as an initial presentation of colorectal cancer a systematic review |
| topic | Rectal prolapse Colorectal cancer Initial presentation Systematic review |
| url | https://doi.org/10.1186/s12885-025-13924-4 |
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