The course of infectious arthritis in a patient with hypogammaglobulinemia
Hypogammaglobulinemia is a condition caused by low levels of immunoglobulins in the blood serum. It can be a manifestation of primary immunodeficiency, characterized by a violation of the production of immunoglobulins, in particular common variable immunodeficiency (CVID). A typical clinical sign of...
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| Language: | Russian |
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IMA-PRESS LLC
2022-08-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/1323 |
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| author | E. A. Savchenko P. A. Glazunov S. S. Bunova E. V. Zhilyaev |
| author_facet | E. A. Savchenko P. A. Glazunov S. S. Bunova E. V. Zhilyaev |
| author_sort | E. A. Savchenko |
| collection | DOAJ |
| description | Hypogammaglobulinemia is a condition caused by low levels of immunoglobulins in the blood serum. It can be a manifestation of primary immunodeficiency, characterized by a violation of the production of immunoglobulins, in particular common variable immunodeficiency (CVID). A typical clinical sign of CVID is various severe infections, among which infectious arthritis is not uncommon. At the same time, the clinical picture of infections can differ significantly from that in individuals with a normal immune response, including the spectrum of infectious arthritis pathogens.The article describes a clinical case of an unusual course of infectious arthritis in a patient with newly diagnosed hypogammaglobulinemia. The peculiar features of the case were a long (more than 1.5 years) course of the disease, without the development of septic complications, no increase in ESR and CRP, recurrence of arthritis after a 2-month course of antibiotic therapy, and the presence of generalized edema. The causes and diagnosis, features of infectious complications, including infectious arthritis, and probable causes of edematous syndrome in CVID are discussed. |
| format | Article |
| id | doaj-art-2ab03043cd73467f937962bd4f4e096f |
| institution | DOAJ |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2022-08-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-2ab03043cd73467f937962bd4f4e096f2025-08-20T03:20:59ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2022-08-01164576210.14412/1996-7012-2022-4-57-622500The course of infectious arthritis in a patient with hypogammaglobulinemiaE. A. Savchenko0P. A. Glazunov1S. S. Bunova2E. V. Zhilyaev3Pirogov Russian National Research Medical University, Ministry of Health of RussiaJSC "European Medical Center"JSC "European Medical Center"; Belgorod State National Research UniversityPirogov Russian National Research Medical University, Ministry of Health of Russia; JSC "European Medical Center"; Russian Medical Academy of Continuing Professional EducationHypogammaglobulinemia is a condition caused by low levels of immunoglobulins in the blood serum. It can be a manifestation of primary immunodeficiency, characterized by a violation of the production of immunoglobulins, in particular common variable immunodeficiency (CVID). A typical clinical sign of CVID is various severe infections, among which infectious arthritis is not uncommon. At the same time, the clinical picture of infections can differ significantly from that in individuals with a normal immune response, including the spectrum of infectious arthritis pathogens.The article describes a clinical case of an unusual course of infectious arthritis in a patient with newly diagnosed hypogammaglobulinemia. The peculiar features of the case were a long (more than 1.5 years) course of the disease, without the development of septic complications, no increase in ESR and CRP, recurrence of arthritis after a 2-month course of antibiotic therapy, and the presence of generalized edema. The causes and diagnosis, features of infectious complications, including infectious arthritis, and probable causes of edematous syndrome in CVID are discussed.https://mrj.ima-press.net/mrj/article/view/1323hypogammaglobulinemiacommon variable immune deficiencyinfectious arthritiswidespread edema |
| spellingShingle | E. A. Savchenko P. A. Glazunov S. S. Bunova E. V. Zhilyaev The course of infectious arthritis in a patient with hypogammaglobulinemia Современная ревматология hypogammaglobulinemia common variable immune deficiency infectious arthritis widespread edema |
| title | The course of infectious arthritis in a patient with hypogammaglobulinemia |
| title_full | The course of infectious arthritis in a patient with hypogammaglobulinemia |
| title_fullStr | The course of infectious arthritis in a patient with hypogammaglobulinemia |
| title_full_unstemmed | The course of infectious arthritis in a patient with hypogammaglobulinemia |
| title_short | The course of infectious arthritis in a patient with hypogammaglobulinemia |
| title_sort | course of infectious arthritis in a patient with hypogammaglobulinemia |
| topic | hypogammaglobulinemia common variable immune deficiency infectious arthritis widespread edema |
| url | https://mrj.ima-press.net/mrj/article/view/1323 |
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