The value of intra-voxel incoherent motion, susceptibility-weighted images and post-contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumor
Abstract Background Our aim to assess the significance of new multi-parametric MRI techniques as intra-voxel incoherent motion (IVIM), T2* perfusion, T1 permeability and susceptibility-weighted images (SWI) in differentiating from recurrent tumor from post treatment changes. Results Forty-five patie...
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| Language: | English |
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SpringerOpen
2025-06-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
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| Online Access: | https://doi.org/10.1186/s43055-025-01478-1 |
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| author | Mena Elerian Youssef Ekladious Mina M. Gerges Samar Ramzy Ragheb |
| author_facet | Mena Elerian Youssef Ekladious Mina M. Gerges Samar Ramzy Ragheb |
| author_sort | Mena Elerian Youssef Ekladious |
| collection | DOAJ |
| description | Abstract Background Our aim to assess the significance of new multi-parametric MRI techniques as intra-voxel incoherent motion (IVIM), T2* perfusion, T1 permeability and susceptibility-weighted images (SWI) in differentiating from recurrent tumor from post treatment changes. Results Forty-five patients were enrolled in the current study, 25 patients with recurrence and 20 with radiation necrosis. As regard the IVIM parameters, the perfusion fraction (f) and the pseudodiffusion (D*) component shows significant difference between radiation changes and recurrent tumor (P value = 0.01). The Ktrans showed significant difference between radiation changes and recurrent tumor (P value = 0.001). The proportion of dark signal intensity on susceptibility-weighted imaging (proSWI) showed significant difference between radiation changes and recurrent tumor (P value = 0.0001), while the diffusion component (D) showed no significant difference between radiation changes and recurrent tumor (P value = 0.282). Conclusions Multi-parametric new techniques as intra-voxel incoherent motion, susceptibility weighted images and post-contrast perfusion studies allow early and accurate differentiation of recurrent tumor from post radiation changes and thus improving the patients overall clinical outcome. |
| format | Article |
| id | doaj-art-2aab070e1f74457a9af10eba6951b982 |
| institution | OA Journals |
| issn | 2090-4762 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj-art-2aab070e1f74457a9af10eba6951b9822025-08-20T02:05:49ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622025-06-0156111410.1186/s43055-025-01478-1The value of intra-voxel incoherent motion, susceptibility-weighted images and post-contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumorMena Elerian Youssef Ekladious0Mina M. Gerges1Samar Ramzy Ragheb2Radiology Department, Faculty of Medicine, Ain Shams UniversityNeurosurgery Department, Faculty of Medicine, Ain Shams UniversityRadiology Department, Faculty of Medicine, Ain Shams UniversityAbstract Background Our aim to assess the significance of new multi-parametric MRI techniques as intra-voxel incoherent motion (IVIM), T2* perfusion, T1 permeability and susceptibility-weighted images (SWI) in differentiating from recurrent tumor from post treatment changes. Results Forty-five patients were enrolled in the current study, 25 patients with recurrence and 20 with radiation necrosis. As regard the IVIM parameters, the perfusion fraction (f) and the pseudodiffusion (D*) component shows significant difference between radiation changes and recurrent tumor (P value = 0.01). The Ktrans showed significant difference between radiation changes and recurrent tumor (P value = 0.001). The proportion of dark signal intensity on susceptibility-weighted imaging (proSWI) showed significant difference between radiation changes and recurrent tumor (P value = 0.0001), while the diffusion component (D) showed no significant difference between radiation changes and recurrent tumor (P value = 0.282). Conclusions Multi-parametric new techniques as intra-voxel incoherent motion, susceptibility weighted images and post-contrast perfusion studies allow early and accurate differentiation of recurrent tumor from post radiation changes and thus improving the patients overall clinical outcome.https://doi.org/10.1186/s43055-025-01478-1Intra-voxel incoherent motion (IVIM)T2* perfusionT1 permeabilitySusceptibility weighted images (SWI)Recurrent brain tumorRadiation necrosis |
| spellingShingle | Mena Elerian Youssef Ekladious Mina M. Gerges Samar Ramzy Ragheb The value of intra-voxel incoherent motion, susceptibility-weighted images and post-contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumor The Egyptian Journal of Radiology and Nuclear Medicine Intra-voxel incoherent motion (IVIM) T2* perfusion T1 permeability Susceptibility weighted images (SWI) Recurrent brain tumor Radiation necrosis |
| title | The value of intra-voxel incoherent motion, susceptibility-weighted images and post-contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumor |
| title_full | The value of intra-voxel incoherent motion, susceptibility-weighted images and post-contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumor |
| title_fullStr | The value of intra-voxel incoherent motion, susceptibility-weighted images and post-contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumor |
| title_full_unstemmed | The value of intra-voxel incoherent motion, susceptibility-weighted images and post-contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumor |
| title_short | The value of intra-voxel incoherent motion, susceptibility-weighted images and post-contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumor |
| title_sort | value of intra voxel incoherent motion susceptibility weighted images and post contrast magnetic resonance perfusion studies in assessment of treatment response to brain tumor |
| topic | Intra-voxel incoherent motion (IVIM) T2* perfusion T1 permeability Susceptibility weighted images (SWI) Recurrent brain tumor Radiation necrosis |
| url | https://doi.org/10.1186/s43055-025-01478-1 |
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