Nanoparticle-in-Hydrogel Delivery System for the Sequential Release of Two Drugs

Nanoparticle-in-Hydrogel Delivery System for the Sequential Release of Two Drugs

Background/Objectives: Glioblastoma is the most common and lethal primary brain tumor. Patients often suffer from tumor- and treatment induced vasogenic edema, with devastating neurological consequences. Intracranial edema is effectively treated with dexamethasone. However, systemic dexamethasone re...

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Bibliographic Details
Main Authors: Demian van Straten, Jaime Fernández Bimbo, Wim E. Hennink, Tina Vermonden, Raymond M. Schiffelers
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
hydrogel
nanoparticle
liposome
micelle
combination therapy
local delivery
Online Access:https://www.mdpi.com/1999-4923/17/1/127
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