Synthesis of Novel Aryl-Substituted Acetylenic Monoterpene Analogues by Sonogashira Coupling

The synthesis of new aryl-substituted acetylenic monoterpene derivatives was carried out by the Sonogashira reaction. The reactions proceed in the presence of PdCl<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub>, CuI and Et<sub>3</sub>N and provide aryl-subst...

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Main Authors: Rinat Gubaidullin, Lyudmila Parfenova
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Chemistry Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4583/16/1/44
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author Rinat Gubaidullin
Lyudmila Parfenova
author_facet Rinat Gubaidullin
Lyudmila Parfenova
author_sort Rinat Gubaidullin
collection DOAJ
description The synthesis of new aryl-substituted acetylenic monoterpene derivatives was carried out by the Sonogashira reaction. The reactions proceed in the presence of PdCl<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub>, CuI and Et<sub>3</sub>N and provide aryl-substituted acetylenic monoterpenes with an isolated yield of 70–82%.
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spelling doaj-art-2a901f82aef24703a32ffd56d5e5f7a82025-08-20T02:24:25ZengMDPI AGChemistry Proceedings2673-45832024-11-011614410.3390/ecsoc-28-20124Synthesis of Novel Aryl-Substituted Acetylenic Monoterpene Analogues by Sonogashira CouplingRinat Gubaidullin0Lyudmila Parfenova1Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences 141 Prospekt Oktyabrya, Ufa 450075, RussiaInstitute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences 141 Prospekt Oktyabrya, Ufa 450075, RussiaThe synthesis of new aryl-substituted acetylenic monoterpene derivatives was carried out by the Sonogashira reaction. The reactions proceed in the presence of PdCl<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub>, CuI and Et<sub>3</sub>N and provide aryl-substituted acetylenic monoterpenes with an isolated yield of 70–82%.https://www.mdpi.com/2673-4583/16/1/44monoterpenescamphorcarvonealkylationreductionSonogashira reaction
spellingShingle Rinat Gubaidullin
Lyudmila Parfenova
Synthesis of Novel Aryl-Substituted Acetylenic Monoterpene Analogues by Sonogashira Coupling
Chemistry Proceedings
monoterpenes
camphor
carvone
alkylation
reduction
Sonogashira reaction
title Synthesis of Novel Aryl-Substituted Acetylenic Monoterpene Analogues by Sonogashira Coupling
title_full Synthesis of Novel Aryl-Substituted Acetylenic Monoterpene Analogues by Sonogashira Coupling
title_fullStr Synthesis of Novel Aryl-Substituted Acetylenic Monoterpene Analogues by Sonogashira Coupling
title_full_unstemmed Synthesis of Novel Aryl-Substituted Acetylenic Monoterpene Analogues by Sonogashira Coupling
title_short Synthesis of Novel Aryl-Substituted Acetylenic Monoterpene Analogues by Sonogashira Coupling
title_sort synthesis of novel aryl substituted acetylenic monoterpene analogues by sonogashira coupling
topic monoterpenes
camphor
carvone
alkylation
reduction
Sonogashira reaction
url https://www.mdpi.com/2673-4583/16/1/44
work_keys_str_mv AT rinatgubaidullin synthesisofnovelarylsubstitutedacetylenicmonoterpeneanaloguesbysonogashiracoupling
AT lyudmilaparfenova synthesisofnovelarylsubstitutedacetylenicmonoterpeneanaloguesbysonogashiracoupling