Transvaginal color Doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancer
Background. To evaluate the role of transvaginal color Doppler ultrasound in monitoring the response to neoadjuvant chemotherapy in patients with locally‐advanced cervical cancer. Methods. Fourteen patients with locally‐advanced cervical cancer, scheduled for neoadjuvant chemotherapy, were investiga...
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| Format: | Article |
| Language: | English |
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Wiley
1997-02-01
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| Series: | Acta Obstetricia et Gynecologica Scandinavica |
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| Online Access: | https://doi.org/10.3109/00016349709050075 |
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| author | Pantaleo Greco Gennaro Cormio Antonella Vimercati Grazia Nacci Giovanni diVagno Giuseppe Loverro Luigi Selvaggi |
| author_facet | Pantaleo Greco Gennaro Cormio Antonella Vimercati Grazia Nacci Giovanni diVagno Giuseppe Loverro Luigi Selvaggi |
| author_sort | Pantaleo Greco |
| collection | DOAJ |
| description | Background. To evaluate the role of transvaginal color Doppler ultrasound in monitoring the response to neoadjuvant chemotherapy in patients with locally‐advanced cervical cancer. Methods. Fourteen patients with locally‐advanced cervical cancer, scheduled for neoadjuvant chemotherapy, were investigated with transvaginal color Doppler ultrasonography before and at the completion of chemotherapy in order to study hemodynamic changes in cervical and intratumoral vessels. Twenty healthy women matched for age and parity served as a control group. Statistical analysis was performed with Student's t test for paired data. Results. Statistically different blood flow recording between patients with cervical cancer and healthy controls could be observed only in intratumoral vessels. A significant increase of RI and PI values, recorded in both cervical artery and intratumoral vessels, have been observed in the group of patients responding to neoadjuvant chemotherapy. In patients with stable disease at the completion of chemotherapy, flow characteristics did not change significantly. Conclusion. Preliminary results of our study suggest that transvaginal color Doppler ultrasound evaluation of flow characteristics in the cervical and intratumoral vessels might be useful in monitoring the response to neoadjuvant chemotherapy in patients with invasive cervical cancer. |
| format | Article |
| id | doaj-art-2a7e0846f5bf488aaf8a4ff67688a829 |
| institution | OA Journals |
| issn | 0001-6349 1600-0412 |
| language | English |
| publishDate | 1997-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Acta Obstetricia et Gynecologica Scandinavica |
| spelling | doaj-art-2a7e0846f5bf488aaf8a4ff67688a8292025-08-20T02:37:29ZengWileyActa Obstetricia et Gynecologica Scandinavica0001-63491600-04121997-02-0176216917210.3109/00016349709050075Transvaginal color Doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancerPantaleo Greco0Gennaro Cormio1Antonella Vimercati2Grazia Nacci3Giovanni diVagno4Giuseppe Loverro5Luigi Selvaggi6department of Obstetrics and Gynecology, University of, Barí, Italydepartment of Obstetrics and Gynecology, University of, Barí, Italydepartment of Obstetrics and Gynecology, University of, Barí, Italydepartment of Obstetrics and Gynecology, University of, Barí, Italydepartment of Obstetrics and Gynecology, University of, Barí, Italydepartment of Obstetrics and Gynecology, University of, Barí, Italydepartment of Obstetrics and Gynecology, University of, Barí, ItalyBackground. To evaluate the role of transvaginal color Doppler ultrasound in monitoring the response to neoadjuvant chemotherapy in patients with locally‐advanced cervical cancer. Methods. Fourteen patients with locally‐advanced cervical cancer, scheduled for neoadjuvant chemotherapy, were investigated with transvaginal color Doppler ultrasonography before and at the completion of chemotherapy in order to study hemodynamic changes in cervical and intratumoral vessels. Twenty healthy women matched for age and parity served as a control group. Statistical analysis was performed with Student's t test for paired data. Results. Statistically different blood flow recording between patients with cervical cancer and healthy controls could be observed only in intratumoral vessels. A significant increase of RI and PI values, recorded in both cervical artery and intratumoral vessels, have been observed in the group of patients responding to neoadjuvant chemotherapy. In patients with stable disease at the completion of chemotherapy, flow characteristics did not change significantly. Conclusion. Preliminary results of our study suggest that transvaginal color Doppler ultrasound evaluation of flow characteristics in the cervical and intratumoral vessels might be useful in monitoring the response to neoadjuvant chemotherapy in patients with invasive cervical cancer.https://doi.org/10.3109/00016349709050075cervical cancerDoppler ultrasoundneoadjuvant chemotherapy |
| spellingShingle | Pantaleo Greco Gennaro Cormio Antonella Vimercati Grazia Nacci Giovanni diVagno Giuseppe Loverro Luigi Selvaggi Transvaginal color Doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancer Acta Obstetricia et Gynecologica Scandinavica cervical cancer Doppler ultrasound neoadjuvant chemotherapy |
| title | Transvaginal color Doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancer |
| title_full | Transvaginal color Doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancer |
| title_fullStr | Transvaginal color Doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancer |
| title_full_unstemmed | Transvaginal color Doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancer |
| title_short | Transvaginal color Doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancer |
| title_sort | transvaginal color doppler ultrasound for monitoring the response to neoadjuvant chemotherapy in advanced cervical cancer |
| topic | cervical cancer Doppler ultrasound neoadjuvant chemotherapy |
| url | https://doi.org/10.3109/00016349709050075 |
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