Mendelian randomization studies of gastric cancer reveal potential risk factors, promising biomarkers and therapeutic targets

Mendelian randomization studies of gastric cancer reveal potential risk factors, promising biomarkers and therapeutic targets

Abstract Objective To further understand the causal relationship between potential risk factors or biomarkers and gastric cancer, we performed an extensive Mendelian randomization (MR) analysis. Methods Genetic instruments were extracted from 486 available traits in 24 subcategories from the MR-Base...

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Bibliographic Details
Main Authors: Maowei He, Yanting Duan, Yuanyan Zhang, Chao Qian, Jiawei Jin
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Gastric cancer
Risk factors
Mendelian randomization
Genetic instruments
Molecular docking
Biomarkers
Online Access:https://doi.org/10.1007/s12672-025-02954-w
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