Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion system
3D bioprinting has emerged as a transformative technology in biomedical engineering, enabling the fabrication of functional tissues through the precise deposition of cell-laden biomaterials. However, the widespread adoption of this technology is constrained by the prohibitive costs of commercial bio...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-08-01
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| Series: | Annals of 3D Printed Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266696412500027X |
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| author | Y. H. Dang Elise Dauzat Asif Istiak Kevin Jackson Victoria Songe Luke West Md Imrul Kayes Md Saiful Islam Tanvir R. Faisal |
| author_facet | Y. H. Dang Elise Dauzat Asif Istiak Kevin Jackson Victoria Songe Luke West Md Imrul Kayes Md Saiful Islam Tanvir R. Faisal |
| author_sort | Y. H. Dang |
| collection | DOAJ |
| description | 3D bioprinting has emerged as a transformative technology in biomedical engineering, enabling the fabrication of functional tissues through the precise deposition of cell-laden biomaterials. However, the widespread adoption of this technology is constrained by the prohibitive costs of commercial bioprinting systems. We present a cost-effective solution through the conversion of an open-source fused deposition modeling (FDM) 3D printer into a direct ink write bioprinter by integrating a peristaltic pump-based extrusion system. The modified dual-extruder system demonstrates successful deposition of hydrogel-based bioinks across varying viscosities, producing well-defined scaffold architectures. The printer's open-source control architecture facilitates retraction capabilities, high-speed movements, and customizable printing parameters, enhancing operational flexibility. This development represents a significant step toward democratizing low-cost bioprinting technology, making it accessible to academic institutions and research facilities with limited resources. |
| format | Article |
| id | doaj-art-2a69971ae4904fa2a6b910298bacadce |
| institution | Kabale University |
| issn | 2666-9641 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of 3D Printed Medicine |
| spelling | doaj-art-2a69971ae4904fa2a6b910298bacadce2025-08-20T03:43:45ZengElsevierAnnals of 3D Printed Medicine2666-96412025-08-011910021210.1016/j.stlm.2025.100212Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion systemY. H. Dang0Elise Dauzat1Asif Istiak2Kevin Jackson3Victoria Songe4Luke West5Md Imrul Kayes6Md Saiful Islam7Tanvir R. Faisal8Department of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USADepartment of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USADepartment of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USADepartment of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USADepartment of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USADepartment of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USADepartment of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USADepartment of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USACorresponding author at: 241 E Lewis St, Mechanical Engineering, University of Louisiana at Lafayette, LA, 70503, USA.; Department of Mechanical Engineering, University of Louisiana at Lafayette, Lafayette, LA 70503, USA3D bioprinting has emerged as a transformative technology in biomedical engineering, enabling the fabrication of functional tissues through the precise deposition of cell-laden biomaterials. However, the widespread adoption of this technology is constrained by the prohibitive costs of commercial bioprinting systems. We present a cost-effective solution through the conversion of an open-source fused deposition modeling (FDM) 3D printer into a direct ink write bioprinter by integrating a peristaltic pump-based extrusion system. The modified dual-extruder system demonstrates successful deposition of hydrogel-based bioinks across varying viscosities, producing well-defined scaffold architectures. The printer's open-source control architecture facilitates retraction capabilities, high-speed movements, and customizable printing parameters, enhancing operational flexibility. This development represents a significant step toward democratizing low-cost bioprinting technology, making it accessible to academic institutions and research facilities with limited resources.http://www.sciencedirect.com/science/article/pii/S266696412500027XBioprinterConverted 3D printerPeristaltic pumpHydrogelBioink |
| spellingShingle | Y. H. Dang Elise Dauzat Asif Istiak Kevin Jackson Victoria Songe Luke West Md Imrul Kayes Md Saiful Islam Tanvir R. Faisal Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion system Annals of 3D Printed Medicine Bioprinter Converted 3D printer Peristaltic pump Hydrogel Bioink |
| title | Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion system |
| title_full | Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion system |
| title_fullStr | Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion system |
| title_full_unstemmed | Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion system |
| title_short | Conversion of an FDM printer to direct ink write 3D bioprinter utilizing an efficient and cost-effective extrusion system |
| title_sort | conversion of an fdm printer to direct ink write 3d bioprinter utilizing an efficient and cost effective extrusion system |
| topic | Bioprinter Converted 3D printer Peristaltic pump Hydrogel Bioink |
| url | http://www.sciencedirect.com/science/article/pii/S266696412500027X |
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