A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements.

A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements.

X-chromosome inactivation, which occurs in female eutherian mammals is controlled by a complex X-linked locus termed the X-inactivation center (XIC). Previously it was proposed that genes of the XIC evolved, at least in part, as a result of pseudogenization of protein-coding genes. In this study we...

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Bibliographic Details
Main Authors: Eugeny A Elisaphenko, Nikolay N Kolesnikov, Alexander I Shevchenko, Igor B Rogozin, Tatyana B Nesterova, Neil Brockdorff, Suren M Zakian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0002521&type=printable
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