Sources of variation in cell-type RNA-Seq profiles.

Sources of variation in cell-type RNA-Seq profiles.

Cell-type specific gene expression profiles are needed for many computational methods operating on bulk RNA-Seq samples, such as deconvolution of cell-type fractions and digital cytometry. However, the gene expression profile of a cell type can vary substantially due to both technical factors and bi...

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Bibliographic Details
Main Authors: Johan Gustafsson, Felix Held, Jonathan L Robinson, Elias Björnson, Rebecka Jörnsten, Jens Nielsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0239495&type=printable
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