Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World Study
<b>Objectives</b>: To evaluate the effectiveness of astigmatism correction between topographic- and manifest-based methods in individuals who underwent second-generation keratorefractive lenticule extraction (KLEx) surgery. <b>Methods</b>: This study was conducted with partic...
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2025-01-01
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| author | Chia-Yi Lee Hung-Chi Chen Shun-Fa Yang Yi-Jen Hsueh Chin-Te Huang Jing-Yang Huang Ie-Bin Lian Chao-Kai Chang |
| author_facet | Chia-Yi Lee Hung-Chi Chen Shun-Fa Yang Yi-Jen Hsueh Chin-Te Huang Jing-Yang Huang Ie-Bin Lian Chao-Kai Chang |
| author_sort | Chia-Yi Lee |
| collection | DOAJ |
| description | <b>Objectives</b>: To evaluate the effectiveness of astigmatism correction between topographic- and manifest-based methods in individuals who underwent second-generation keratorefractive lenticule extraction (KLEx) surgery. <b>Methods</b>: This study was conducted with participants who underwent second-generation KLEx surgery. After exclusion, there were 46 and 43 participants in the manifest and topographic groups, respectively. The main outcomes were postoperative uncorrected distance visual acuity (UDVA), spherical equivalent (SE), and residual astigmatism. The independent T-test and generalized estimate equation were used to investigate differences between the two groups. <b>Results</b>: Three months postoperatively, UDVA was 0.02 ± 0.04 in the manifest group and 0.00 ± 0.06 in the topographic group which also revealed no significant difference (<i>p</i> = 0.155). Also, the SE value in the two groups three months postoperatively was statistically similar (−0.57 ± 0.48D versus −0.63 ± 0.62D, <i>p</i> = 0.574). The final residual astigmatism was −0.26 ± 0.27 in the topographic group which was significantly lower than the −0.51 ± 0.40 in the manifest group (<i>p</i> < 0.001). Moreover, the amplitude of astigmatism change was significantly lower in the topographic group (<i>p</i> = 0.002). In the subgroup analysis, UDVA and residual astigmatism were significantly better in the topographic group than in the manifest group (both <i>p</i> < 0.05). <b>Conclusions</b>: The topographic-based method represents a better astigmatism correction than the manifest-based method in second-generation KLEx surgery, especially in the low astigmatism population. |
| format | Article |
| id | doaj-art-2a58902974194ef1904df0a177a44c79 |
| institution | Kabale University |
| issn | 2075-4418 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj-art-2a58902974194ef1904df0a177a44c792025-01-10T13:16:43ZengMDPI AGDiagnostics2075-44182025-01-011519810.3390/diagnostics15010098Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World StudyChia-Yi Lee0Hung-Chi Chen1Shun-Fa Yang2Yi-Jen Hsueh3Chin-Te Huang4Jing-Yang Huang5Ie-Bin Lian6Chao-Kai Chang7Institute of Medicine, Chung Shan Medical University, Taichung 40201, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, TaiwanInstitute of Medicine, Chung Shan Medical University, Taichung 40201, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan 33305, TaiwanDepartment of Ophthalmology, Chung Shan Medical University Hospital, Taichung 40201, TaiwanDepartment of Medical Research, Chung Shan Medical University Hospital, Taichung 40201, TaiwanInstitute of Statistical and Information Science, National Changhua University of Education, Chunghua 50007, TaiwanNobel Eye Institute, Taipei 10041, Taiwan<b>Objectives</b>: To evaluate the effectiveness of astigmatism correction between topographic- and manifest-based methods in individuals who underwent second-generation keratorefractive lenticule extraction (KLEx) surgery. <b>Methods</b>: This study was conducted with participants who underwent second-generation KLEx surgery. After exclusion, there were 46 and 43 participants in the manifest and topographic groups, respectively. The main outcomes were postoperative uncorrected distance visual acuity (UDVA), spherical equivalent (SE), and residual astigmatism. The independent T-test and generalized estimate equation were used to investigate differences between the two groups. <b>Results</b>: Three months postoperatively, UDVA was 0.02 ± 0.04 in the manifest group and 0.00 ± 0.06 in the topographic group which also revealed no significant difference (<i>p</i> = 0.155). Also, the SE value in the two groups three months postoperatively was statistically similar (−0.57 ± 0.48D versus −0.63 ± 0.62D, <i>p</i> = 0.574). The final residual astigmatism was −0.26 ± 0.27 in the topographic group which was significantly lower than the −0.51 ± 0.40 in the manifest group (<i>p</i> < 0.001). Moreover, the amplitude of astigmatism change was significantly lower in the topographic group (<i>p</i> = 0.002). In the subgroup analysis, UDVA and residual astigmatism were significantly better in the topographic group than in the manifest group (both <i>p</i> < 0.05). <b>Conclusions</b>: The topographic-based method represents a better astigmatism correction than the manifest-based method in second-generation KLEx surgery, especially in the low astigmatism population.https://www.mdpi.com/2075-4418/15/1/98keratorefractive lenticule extractionvisumax 800smile prouncorrected distance visual acuityastigmatism |
| spellingShingle | Chia-Yi Lee Hung-Chi Chen Shun-Fa Yang Yi-Jen Hsueh Chin-Te Huang Jing-Yang Huang Ie-Bin Lian Chao-Kai Chang Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World Study Diagnostics keratorefractive lenticule extraction visumax 800 smile pro uncorrected distance visual acuity astigmatism |
| title | Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World Study |
| title_full | Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World Study |
| title_fullStr | Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World Study |
| title_full_unstemmed | Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World Study |
| title_short | Comparison Between Topographic-Based and Manifest-Based Astigmatism Corrections in the Second (Visumax 800)-Generation Keratorefractive Lenticule Extraction Surgery: A Real-World Study |
| title_sort | comparison between topographic based and manifest based astigmatism corrections in the second visumax 800 generation keratorefractive lenticule extraction surgery a real world study |
| topic | keratorefractive lenticule extraction visumax 800 smile pro uncorrected distance visual acuity astigmatism |
| url | https://www.mdpi.com/2075-4418/15/1/98 |
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