Olfactory disorders in patients with chronic rhinosinusitis in Kinshasa, Democratic Republic of the Congo: A cross-sectional study
Introduction Approximately three-quarters of patients with chronic rhinosinusitis (CRS) develop an olfactory disorder (OD). Due to its gradual onset and subtle nature, many CRS patients are unaware of their OD, making its assessment and prevalence difficult. Objective This study aimed to a...
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Orapuh, Inc.
2025-01-01
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| author | Yasmin Nsunzu Tshingamb Sympho Junior Mpiana Patrick Sekele Marob Ndjock Emile Kayembe Eric Banza Lukoji Alain Ntumba Malemba Auguste O. Omadjela Dieudonné T. Nyembue |
| author_facet | Yasmin Nsunzu Tshingamb Sympho Junior Mpiana Patrick Sekele Marob Ndjock Emile Kayembe Eric Banza Lukoji Alain Ntumba Malemba Auguste O. Omadjela Dieudonné T. Nyembue |
| author_sort | Yasmin Nsunzu Tshingamb |
| collection | DOAJ |
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Introduction
Approximately three-quarters of patients with chronic rhinosinusitis (CRS) develop an olfactory disorder (OD). Due to its gradual onset and subtle nature, many CRS patients are unaware of their OD, making its assessment and prevalence difficult.
Objective
This study aimed to assess the frequency of ODs and the characteristics of CRS patients in a hospital setting in Kinshasa.
Methods
This was a cross-sectional and analytical study involving 105 CRS patients in two medical facilities in Kinshasa. Eligible patients were aged ≥18 years, diagnosed with CRS, had completed primary education, and provided informed consent. The ASOF questionnaire and the Sniffin' Sticks Test (SST) were used for subjective and/or objective olfactory assessment. Univariate analyses were performed to describe statistics for variables of interest. Frequencies were calculated for qualitative variables, while the mean (SD) was reported for quantitative variables. Proportions were compared using the Chi-square test, and the Student's t-test was used to compare means.
Results
The average age of patients was 40.3 ± 1.4 years, with a higher number of females. Allergic comorbidities were the most commonly reported in patient histories. Subjectively, only 22.9% of patients reported an altered sense of smell; however, using the SST, 63.8% of CRS patients were found to have an OD, primarily hyposmia. All mean scores for subjective and objective olfactory assessments were significantly higher (p < 0.001) among CRS patients with OD compared to those without. Additionally, the mean VAS level for loss of smell was higher in CRS patients with OD (p < 0.001). Patients with OD were significantly older than those without (42.6 ± 5.3 years vs. 36.3 ± 13.3 years; p = 0.035).
Conclusion
This study demonstrates that ODs are common in CRS, particularly among older patients. Olfactory assessment should be implemented to ensure effective diagnosis and management of rhinological conditions.
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| format | Article |
| id | doaj-art-2a4a93ca20e44c1c803f652aec4b7f54 |
| institution | Kabale University |
| issn | 2644-3740 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Orapuh, Inc. |
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| series | Orapuh Journal |
| spelling | doaj-art-2a4a93ca20e44c1c803f652aec4b7f542025-01-30T06:12:05ZengOrapuh, Inc.Orapuh Journal2644-37402025-01-016110.4314/orapj.v6i1.10Olfactory disorders in patients with chronic rhinosinusitis in Kinshasa, Democratic Republic of the Congo: A cross-sectional study Yasmin Nsunzu Tshingamb0 Sympho Junior Mpiana1Patrick Sekele Marob Ndjock 2Emile Kayembe3Eric Banza Lukoji 4Alain Ntumba Malemba 5Auguste O. Omadjela6Dieudonné T. Nyembue7University of Kinshasa, Kinshasa XI, Democratic Republic of the CongoUniversity of Kinshasa, Kinshasa XI, Democratic Republic of the CongoUniversity of Kinshasa, Kinshasa XI, Democratic Republic of the CongoUniversity of Kinshasa, Kinshasa XI, Democratic Republic of the CongoUniversity of Kinshasa, Kinshasa XI, Democratic Republic of the CongoUniversity of Kinshasa, Kinshasa XI, Democratic Republic of the CongoSaint Joseph Hospital of Kinshasa, Kinshasa, Democratic Republic of the CongoUniversity of Kinshasa, Kinshasa XI, Democratic Republic of the Congo Introduction Approximately three-quarters of patients with chronic rhinosinusitis (CRS) develop an olfactory disorder (OD). Due to its gradual onset and subtle nature, many CRS patients are unaware of their OD, making its assessment and prevalence difficult. Objective This study aimed to assess the frequency of ODs and the characteristics of CRS patients in a hospital setting in Kinshasa. Methods This was a cross-sectional and analytical study involving 105 CRS patients in two medical facilities in Kinshasa. Eligible patients were aged ≥18 years, diagnosed with CRS, had completed primary education, and provided informed consent. The ASOF questionnaire and the Sniffin' Sticks Test (SST) were used for subjective and/or objective olfactory assessment. Univariate analyses were performed to describe statistics for variables of interest. Frequencies were calculated for qualitative variables, while the mean (SD) was reported for quantitative variables. Proportions were compared using the Chi-square test, and the Student's t-test was used to compare means. Results The average age of patients was 40.3 ± 1.4 years, with a higher number of females. Allergic comorbidities were the most commonly reported in patient histories. Subjectively, only 22.9% of patients reported an altered sense of smell; however, using the SST, 63.8% of CRS patients were found to have an OD, primarily hyposmia. All mean scores for subjective and objective olfactory assessments were significantly higher (p < 0.001) among CRS patients with OD compared to those without. Additionally, the mean VAS level for loss of smell was higher in CRS patients with OD (p < 0.001). Patients with OD were significantly older than those without (42.6 ± 5.3 years vs. 36.3 ± 13.3 years; p = 0.035). Conclusion This study demonstrates that ODs are common in CRS, particularly among older patients. Olfactory assessment should be implemented to ensure effective diagnosis and management of rhinological conditions. https://orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/article/view/347Olfactory disorderschronic rhinosinusitispatientsDemocratic Republic of the Congo |
| spellingShingle | Yasmin Nsunzu Tshingamb Sympho Junior Mpiana Patrick Sekele Marob Ndjock Emile Kayembe Eric Banza Lukoji Alain Ntumba Malemba Auguste O. Omadjela Dieudonné T. Nyembue Olfactory disorders in patients with chronic rhinosinusitis in Kinshasa, Democratic Republic of the Congo: A cross-sectional study Orapuh Journal Olfactory disorders chronic rhinosinusitis patients Democratic Republic of the Congo |
| title | Olfactory disorders in patients with chronic rhinosinusitis in Kinshasa, Democratic Republic of the Congo: A cross-sectional study |
| title_full | Olfactory disorders in patients with chronic rhinosinusitis in Kinshasa, Democratic Republic of the Congo: A cross-sectional study |
| title_fullStr | Olfactory disorders in patients with chronic rhinosinusitis in Kinshasa, Democratic Republic of the Congo: A cross-sectional study |
| title_full_unstemmed | Olfactory disorders in patients with chronic rhinosinusitis in Kinshasa, Democratic Republic of the Congo: A cross-sectional study |
| title_short | Olfactory disorders in patients with chronic rhinosinusitis in Kinshasa, Democratic Republic of the Congo: A cross-sectional study |
| title_sort | olfactory disorders in patients with chronic rhinosinusitis in kinshasa democratic republic of the congo a cross sectional study |
| topic | Olfactory disorders chronic rhinosinusitis patients Democratic Republic of the Congo |
| url | https://orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/article/view/347 |
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