The Role of Human Endogenous Retroviruses in the Initiation and Progression of Melanoma

The Role of Human Endogenous Retroviruses in the Initiation and Progression of Melanoma

Human endogenous retroviruses (HERVs), as remnants of ancient exogenous retroviruses in the human genome, have received increased attention regarding their pathogenic effects caused by abnormal activation. In normal somatic cells, HERVs are tightly regulated by epigenetic mechanisms and are rarely e...

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Bibliographic Details
Main Authors: Yao Lin, Rosanna Rita Satta, Elena Rita Simula, Shijie Tang, Paola Molicotti, Antonio Cossu, Corrado Rubino, Leonardo Antonio Sechi
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
human endogenous retrovirus
melanoma
epigenetic dysregulation
immune response
treatment
Online Access:https://www.mdpi.com/2227-9059/13/7/1662
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