EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE
Aim. To study molecular effects of tiotriazoline in 30 patients with stable angina I-III functional class.Material and methods. Comparison of molecular effects of cardioprotection is done based on dynamics of exercise tolerance dynamics, and via proteomic methods of investigation, questionnaires ass...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2016-06-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/409 |
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| author | E. A. Kartashova A. A. Kastanyan M. I. Nazheva A. Yu. Zhulitov E. I. Zheleznyak |
| author_facet | E. A. Kartashova A. A. Kastanyan M. I. Nazheva A. Yu. Zhulitov E. I. Zheleznyak |
| author_sort | E. A. Kartashova |
| collection | DOAJ |
| description | Aim. To study molecular effects of tiotriazoline in 30 patients with stable angina I-III functional class.Material and methods. Comparison of molecular effects of cardioprotection is done based on dynamics of exercise tolerance dynamics, and via proteomic methods of investigation, questionnaires assessment of life quality in patients with ischemic heart disease (IHD).Results. It was found, that tiotriazoline improves exercise tolerance, shows strong cardioprotective effect that includes antioxidant and cytoprotection effects in IHD patients.Conclusion. Tiotriazoline helps to reduce the mean number of angina attacks in IHD patients, as to improve mean functional class. |
| format | Article |
| id | doaj-art-2a287f12a2354c13bdf7a98d53a6ab5a |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2016-06-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-2a287f12a2354c13bdf7a98d53a6ab5a2025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252016-06-01153253010.15829/1728-8800-2016-3-25-30336EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASEE. A. Kartashova0A. A. Kastanyan1M. I. Nazheva2A. Yu. Zhulitov3E. I. Zheleznyak4Rostov State Medical University, Rostov-on-DonRostov State Medical University, Rostov-on-DonRostov State Medical University, Rostov-on-DonRostov State Medical University, Rostov-on-DonRostov State Medical University, Rostov-on-DonAim. To study molecular effects of tiotriazoline in 30 patients with stable angina I-III functional class.Material and methods. Comparison of molecular effects of cardioprotection is done based on dynamics of exercise tolerance dynamics, and via proteomic methods of investigation, questionnaires assessment of life quality in patients with ischemic heart disease (IHD).Results. It was found, that tiotriazoline improves exercise tolerance, shows strong cardioprotective effect that includes antioxidant and cytoprotection effects in IHD patients.Conclusion. Tiotriazoline helps to reduce the mean number of angina attacks in IHD patients, as to improve mean functional class.https://cardiovascular.elpub.ru/jour/article/view/409tiotriazolineischemic heart diseaseexercise tolerancecytochemistryproteomics |
| spellingShingle | E. A. Kartashova A. A. Kastanyan M. I. Nazheva A. Yu. Zhulitov E. I. Zheleznyak EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE Кардиоваскулярная терапия и профилактика tiotriazoline ischemic heart disease exercise tolerance cytochemistry proteomics |
| title | EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE |
| title_full | EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE |
| title_fullStr | EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE |
| title_full_unstemmed | EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE |
| title_short | EFFECTIVENESS OF TIOTRIAZOLINE IN COMPLEX THERAPY OF ISCHEMIC HEART DISEASE |
| title_sort | effectiveness of tiotriazoline in complex therapy of ischemic heart disease |
| topic | tiotriazoline ischemic heart disease exercise tolerance cytochemistry proteomics |
| url | https://cardiovascular.elpub.ru/jour/article/view/409 |
| work_keys_str_mv | AT eakartashova effectivenessoftiotriazolineincomplextherapyofischemicheartdisease AT aakastanyan effectivenessoftiotriazolineincomplextherapyofischemicheartdisease AT minazheva effectivenessoftiotriazolineincomplextherapyofischemicheartdisease AT ayuzhulitov effectivenessoftiotriazolineincomplextherapyofischemicheartdisease AT eizheleznyak effectivenessoftiotriazolineincomplextherapyofischemicheartdisease |