Consistent genes associated with structural changes in clinical Alzheimer’s disease spectrum

Consistent genes associated with structural changes in clinical Alzheimer’s disease spectrum

BackgroundPrevious studies have demonstrated widespread brain neurodegeneration in Alzheimer’s disease (AD). However, the neurobiological and pathogenic substrates underlying this structural atrophy across the AD spectrum remain largely understood.MethodsIn this study, we obtained structural MRI dat...

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Bibliographic Details
Main Authors: Yingqi Lu, Xiaodong Zhang, Liyu Hu, Qinxiu Cheng, Zhewei Zhang, Haoran Zhang, Zhuoran Xie, Yiheng Gao, Dezhi Cao, Shangjie Chen, Jinping Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
mild cognitive impairments
gray matter volume
gene expression
enrichment analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1376288/full
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