FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE)
The reaction of formylation by Vilsmeier - Haack was held. The effect of excess phosphorus oxychloride in the direction of the reaction. Optimal conditions were conducting formylation reaction to obtain a single compound with a high yield. The result of the reaction product mixture was conducted chr...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
|
| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/323 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850046999213113344 |
|---|---|
| author | E. S. Ofitserova A. A. Shklyarenko I. P. Yakovlev E. V. Fedorova |
| author_facet | E. S. Ofitserova A. A. Shklyarenko I. P. Yakovlev E. V. Fedorova |
| author_sort | E. S. Ofitserova |
| collection | DOAJ |
| description | The reaction of formylation by Vilsmeier - Haack was held. The effect of excess phosphorus oxychloride in the direction of the reaction. Optimal conditions were conducting formylation reaction to obtain a single compound with a high yield. The result of the reaction product mixture was conducted chromatographic separation on a column packed with silica gel 60 Silica. |
| format | Article |
| id | doaj-art-2a1b3136a5604a25915dba9302455e9f |
| institution | DOAJ |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-2a1b3136a5604a25915dba9302455e9f2025-08-20T02:54:19ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101112114323FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE)E. S. Ofitserova0A. A. Shklyarenko1I. P. Yakovlev2E. V. Fedorova3Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Chemical-Pharmaceutical Academy" of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Chemical-Pharmaceutical Academy" of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Chemical-Pharmaceutical Academy" of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Chemical-Pharmaceutical Academy" of the Ministry of Health of the Russian FederationThe reaction of formylation by Vilsmeier - Haack was held. The effect of excess phosphorus oxychloride in the direction of the reaction. Optimal conditions were conducting formylation reaction to obtain a single compound with a high yield. The result of the reaction product mixture was conducted chromatographic separation on a column packed with silica gel 60 Silica.https://www.pharmjournal.ru/jour/article/view/323formylationvilsmeier - haack reagentnucleophilic substitution |
| spellingShingle | E. S. Ofitserova A. A. Shklyarenko I. P. Yakovlev E. V. Fedorova FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) Разработка и регистрация лекарственных средств formylation vilsmeier - haack reagent nucleophilic substitution |
| title | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_full | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_fullStr | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_full_unstemmed | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_short | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_sort | formylation of 2 methylthio pyrimdine 4 6 diol in the reactio conditions of vilsmeier haak short message |
| topic | formylation vilsmeier - haack reagent nucleophilic substitution |
| url | https://www.pharmjournal.ru/jour/article/view/323 |
| work_keys_str_mv | AT esofitserova formylationof2methylthiopyrimdine46diolinthereactioconditionsofvilsmeierhaakshortmessage AT aashklyarenko formylationof2methylthiopyrimdine46diolinthereactioconditionsofvilsmeierhaakshortmessage AT ipyakovlev formylationof2methylthiopyrimdine46diolinthereactioconditionsofvilsmeierhaakshortmessage AT evfedorova formylationof2methylthiopyrimdine46diolinthereactioconditionsofvilsmeierhaakshortmessage |