<i>ABCB1</i> Polymorphism Is Associated with Higher Carbamazepine Clearance in Children

<i>ABCB1</i> Polymorphism Is Associated with Higher Carbamazepine Clearance in Children

The aim of our study was to investigate the role of <i>ABCB1</i> polymorphism in the pharmacokinetics of carbamazepine (CBZ) in children. The study enrolled 47 Serbian pediatric epileptic patients on CBZ treatment. Genotyping for <i>ABCB1</i> 1236C<T (rs1128503), 2677G<...

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Main Authors: Natasa Djordjevic, Jelena Cukic, Dragana Dragas Milovanovic, Marija Radovanovic, Ivan Radosavljevic, Jelena Vuckovic Filipovic, Slobodan Obradovic, Dejan Baskic, Jasmina R. Milovanovic, Slobodan Jankovic, Dragan Milovanovic
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pediatric Reports
Subjects:
<i>ABCB1</i>
genetic polymorphism
carbamazepine
population pharmacokinetics
children
Online Access:https://www.mdpi.com/2036-7503/17/1/10
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