CD133 defines hair-inductive cells in the dermal papilla

CD133 defines hair-inductive cells in the dermal papilla

Abstract A major contributing factor to the failure of cell-based human hair follicle (HF) engineering is our inability to cultivate highly specialized, inductive mesenchymal fibroblasts, which reside in a unique niche at the HF base, called the dermal papilla (DP). We and other groups have discover...

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Bibliographic Details
Main Authors: Huangying Zhao, Linli Zhou, Lindsey G. Siegfried, Steven Boyce, Dorothy Supp, Thomas Andl, Yuhang Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Hair follicle
Tissue engineering
Keratinocytes
Fibroblasts
Online Access:https://doi.org/10.1038/s41598-025-05487-y
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