Comparative Analysis of Pattern of Symptoms of Chest Pain in Patients with and without Diabetes: A Systematic Review

Background: Chest pain is a key indicator and is one of the most frequent complaints in hospital settings. However, atypical presentations of chest pain are often associated with various diseases. The symptoms of chest pain can be particularly ambiguous due to various factors, including gender, diab...

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Main Authors: Syed Azizur Rahman, Satwat Maitra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Journal of Diabetology
Subjects:
Online Access:https://doi.org/10.4103/jod.jod_173_24
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author Syed Azizur Rahman
Satwat Maitra
author_facet Syed Azizur Rahman
Satwat Maitra
author_sort Syed Azizur Rahman
collection DOAJ
description Background: Chest pain is a key indicator and is one of the most frequent complaints in hospital settings. However, atypical presentations of chest pain are often associated with various diseases. The symptoms of chest pain can be particularly ambiguous due to various factors, including gender, diabetes mellitus (DM), and other clinical conditions. Thus, this review performed a comparative analysis of patterns of chest pain in patients with and without DM. Materials and Methods: The review was carried out using electronic databases including PubMed, Scopus, Wiley, and Google Scholar. The studies which were available in the last 10 years from January 2013 to December 2023 were considered. Moreover, the included studies were evaluated using the RevMan 5.4 to analyze the risk of bias. Results: Ten studies were incorporated. The comparative analysis of chest pain patterns reveals that diabetic patients often experience atypical symptoms compared to non-diabetic individuals. The assessment of risks in the study revealed that 58.33% were categorized as having a low risk, while 20% had an unclear risk and 71.67% of cases were classified as not applicable. Conclusion: Chest pain was more prevalent in non-diabetic patients, particularly in AMI and ACS, where they typically presented with classic symptoms. Diabetic patients presented atypical symptoms, such as dyspnea, shoulder pain, gastric discomfort, and cold sweats, complicating timely diagnosis. Comorbidities such as hypertension and angina in diabetic patients further obscured symptom interpretation, increasing the risk of delayed recognition and poorer outcomes.
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spelling doaj-art-2a12c3f88e194c96bd1a80c2a475e8dc2025-08-20T02:31:40ZengWolters Kluwer Medknow PublicationsJournal of Diabetology2078-76852025-04-0116211512210.4103/jod.jod_173_24Comparative Analysis of Pattern of Symptoms of Chest Pain in Patients with and without Diabetes: A Systematic ReviewSyed Azizur RahmanSatwat MaitraBackground: Chest pain is a key indicator and is one of the most frequent complaints in hospital settings. However, atypical presentations of chest pain are often associated with various diseases. The symptoms of chest pain can be particularly ambiguous due to various factors, including gender, diabetes mellitus (DM), and other clinical conditions. Thus, this review performed a comparative analysis of patterns of chest pain in patients with and without DM. Materials and Methods: The review was carried out using electronic databases including PubMed, Scopus, Wiley, and Google Scholar. The studies which were available in the last 10 years from January 2013 to December 2023 were considered. Moreover, the included studies were evaluated using the RevMan 5.4 to analyze the risk of bias. Results: Ten studies were incorporated. The comparative analysis of chest pain patterns reveals that diabetic patients often experience atypical symptoms compared to non-diabetic individuals. The assessment of risks in the study revealed that 58.33% were categorized as having a low risk, while 20% had an unclear risk and 71.67% of cases were classified as not applicable. Conclusion: Chest pain was more prevalent in non-diabetic patients, particularly in AMI and ACS, where they typically presented with classic symptoms. Diabetic patients presented atypical symptoms, such as dyspnea, shoulder pain, gastric discomfort, and cold sweats, complicating timely diagnosis. Comorbidities such as hypertension and angina in diabetic patients further obscured symptom interpretation, increasing the risk of delayed recognition and poorer outcomes.https://doi.org/10.4103/jod.jod_173_24acute coronary syndromechest paindiabetes mellitusmyocardial infarctionnon-diabetic patients
spellingShingle Syed Azizur Rahman
Satwat Maitra
Comparative Analysis of Pattern of Symptoms of Chest Pain in Patients with and without Diabetes: A Systematic Review
Journal of Diabetology
acute coronary syndrome
chest pain
diabetes mellitus
myocardial infarction
non-diabetic patients
title Comparative Analysis of Pattern of Symptoms of Chest Pain in Patients with and without Diabetes: A Systematic Review
title_full Comparative Analysis of Pattern of Symptoms of Chest Pain in Patients with and without Diabetes: A Systematic Review
title_fullStr Comparative Analysis of Pattern of Symptoms of Chest Pain in Patients with and without Diabetes: A Systematic Review
title_full_unstemmed Comparative Analysis of Pattern of Symptoms of Chest Pain in Patients with and without Diabetes: A Systematic Review
title_short Comparative Analysis of Pattern of Symptoms of Chest Pain in Patients with and without Diabetes: A Systematic Review
title_sort comparative analysis of pattern of symptoms of chest pain in patients with and without diabetes a systematic review
topic acute coronary syndrome
chest pain
diabetes mellitus
myocardial infarction
non-diabetic patients
url https://doi.org/10.4103/jod.jod_173_24
work_keys_str_mv AT syedazizurrahman comparativeanalysisofpatternofsymptomsofchestpaininpatientswithandwithoutdiabetesasystematicreview
AT satwatmaitra comparativeanalysisofpatternofsymptomsofchestpaininpatientswithandwithoutdiabetesasystematicreview