Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewer
ObjectiveTo explore the research hotspots and development trends in the field of cancer treatment in the past decade. MethodsThe CNKI and Web of Science Core Collection databases were searched for Chinese and English articles related to cancer treatment published over the last 10 years. Bibliometric...
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| Format: | Article |
| Language: | zho |
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Magazine House of Cancer Research on Prevention and Treatment
2025-04-01
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| Series: | Zhongliu Fangzhi Yanjiu |
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| Online Access: | http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.0959 |
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| author | Yuhang FANG Chuchu ZHANG Bailu SUI Yan WANG Runxi WANG Yu CHEN Xinhe YUAN Hongjun YANG Ying ZHANG |
| author_facet | Yuhang FANG Chuchu ZHANG Bailu SUI Yan WANG Runxi WANG Yu CHEN Xinhe YUAN Hongjun YANG Ying ZHANG |
| author_sort | Yuhang FANG |
| collection | DOAJ |
| description | ObjectiveTo explore the research hotspots and development trends in the field of cancer treatment in the past decade. MethodsThe CNKI and Web of Science Core Collection databases were searched for Chinese and English articles related to cancer treatment published over the last 10 years. Bibliometric research methods were employed, including keyword cluster analysis of published literature. ResultsA total of 45 455 Chinese articles and 866 958 English articles were retrieved. Combining the visualization analysis results and the current research dilemma of tumor treatment revealed that the current research hotspots of tumor treatment domestically and internationally can primarily focus on four key areas. In the realm of targeted therapy, efforts are directed towards the discovery of new drug targets, overcoming resistance to targeted therapy, and the development of monoclonal antibodies and antibody–drug conjugates. In the field of immunotherapy, the emphasis lies in enhancing the response rate to immune checkpoint inhibitors, determining the mechanisms behind resistance to immunotherapy, and improving the safety of treatment. The research in traditional Chinese medicine (TCM) covers evidence-based evaluation studies on TCM treatment, the identification of populations that can gain the most benefit from TCM, and strategies for improving the quality of life. In the area of novel drug development, cutting-edge technologies, such as organoid-based screening for anticancer drugs, synthetic biology, and artificial intelligence, are under investigation. ConclusionNew targeted drugs, immune efficacy improvement, multidisciplinary integration, nano-delivery, and TCM innovation are the key research directions in the field of tumor therapy in the future. |
| format | Article |
| id | doaj-art-2a1256a493b64f8899ff0d9f0da7fb8f |
| institution | OA Journals |
| issn | 1000-8578 |
| language | zho |
| publishDate | 2025-04-01 |
| publisher | Magazine House of Cancer Research on Prevention and Treatment |
| record_format | Article |
| series | Zhongliu Fangzhi Yanjiu |
| spelling | doaj-art-2a1256a493b64f8899ff0d9f0da7fb8f2025-08-20T02:16:09ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782025-04-0152429730410.3971/j.issn.1000-8578.2025.24.095920240959Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewerYuhang FANG0Chuchu ZHANG1Bailu SUI2Yan WANG3Runxi WANG4Yu CHEN5Xinhe YUAN6Hongjun YANG7Ying ZHANG8Department of Oncology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaInstitute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, ChinaDepartment of Oncology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Oncology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Oncology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Oncology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaDepartment of Oncology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, ChinaDepartment of Oncology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, ChinaObjectiveTo explore the research hotspots and development trends in the field of cancer treatment in the past decade. MethodsThe CNKI and Web of Science Core Collection databases were searched for Chinese and English articles related to cancer treatment published over the last 10 years. Bibliometric research methods were employed, including keyword cluster analysis of published literature. ResultsA total of 45 455 Chinese articles and 866 958 English articles were retrieved. Combining the visualization analysis results and the current research dilemma of tumor treatment revealed that the current research hotspots of tumor treatment domestically and internationally can primarily focus on four key areas. In the realm of targeted therapy, efforts are directed towards the discovery of new drug targets, overcoming resistance to targeted therapy, and the development of monoclonal antibodies and antibody–drug conjugates. In the field of immunotherapy, the emphasis lies in enhancing the response rate to immune checkpoint inhibitors, determining the mechanisms behind resistance to immunotherapy, and improving the safety of treatment. The research in traditional Chinese medicine (TCM) covers evidence-based evaluation studies on TCM treatment, the identification of populations that can gain the most benefit from TCM, and strategies for improving the quality of life. In the area of novel drug development, cutting-edge technologies, such as organoid-based screening for anticancer drugs, synthetic biology, and artificial intelligence, are under investigation. ConclusionNew targeted drugs, immune efficacy improvement, multidisciplinary integration, nano-delivery, and TCM innovation are the key research directions in the field of tumor therapy in the future.http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.0959tumor therapytargeted therapyimmunotherapytraditional chinese medicine therapynew drug development and researchbibliometrics |
| spellingShingle | Yuhang FANG Chuchu ZHANG Bailu SUI Yan WANG Runxi WANG Yu CHEN Xinhe YUAN Hongjun YANG Ying ZHANG Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewer Zhongliu Fangzhi Yanjiu tumor therapy targeted therapy immunotherapy traditional chinese medicine therapy new drug development and research bibliometrics |
| title | Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewer |
| title_full | Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewer |
| title_fullStr | Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewer |
| title_full_unstemmed | Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewer |
| title_short | Visualization Analysis of Research Hotspots and Trends in Field of Tumor Therapy Based on CiteSpace and VOSviewer |
| title_sort | visualization analysis of research hotspots and trends in field of tumor therapy based on citespace and vosviewer |
| topic | tumor therapy targeted therapy immunotherapy traditional chinese medicine therapy new drug development and research bibliometrics |
| url | http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.0959 |
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