Inherited variants in regulatory T cell genes and outcome of ovarian cancer.

Inherited variants in regulatory T cell genes and outcome of ovarian cancer.

Although ovarian cancer is the most lethal of gynecologic malignancies, wide variation in outcome following conventional therapy continues to exist. The presence of tumor-infiltrating regulatory T cells (Tregs) has a role in outcome of this disease, and a growing body of data supports the existence...

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Main Authors: Ellen L Goode, Melissa DeRycke, Kimberly R Kalli, Ann L Oberg, Julie M Cunningham, Matthew J Maurer, Brooke L Fridley, Sebastian M Armasu, Daniel J Serie, Priya Ramar, Krista Goergen, Robert A Vierkant, David N Rider, Hugues Sicotte, Chen Wang, Boris Winterhoff, Catherine M Phelan, Joellen M Schildkraut, Rachel P Weber, Ed Iversen, Andrew Berchuck, Rebecca Sutphen, Michael J Birrer, Shalaka Hampras, Leah Preus, Simon A Gayther, Susan J Ramus, Nicolas Wentzensen, Hannah P Yang, Montserrat Garcia-Closas, Honglin Song, Jonathan Tyrer, Paul P D Pharoah, Gottfried Konecny, Thomas A Sellers, Roberta B Ness, Lara E Sucheston, Kunle Odunsi, Lynn C Hartmann, Kirsten B Moysich, Keith L Knutson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0053903&type=printable
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