Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT
Abstract Although occupational exposure to radiation and organic solvents has been proven to increase the chance of developing thyroid disease, one of the leading endocrine disorders, much less is known about the potential risk factor of vibration exposure. Thus, this study aimed to examine the rela...
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| Format: | Article |
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Springer
2021-06-01
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| Series: | Aerosol and Air Quality Research |
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| Online Access: | https://doi.org/10.4209/aaqr.210085 |
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| author | Bibo Yuan Citlalli Osorio-Yáñez Junkai Fang Lei Zhao Ander Wilson Marco Sanchez-Guerra Hongbin Liu Peng-Hui Li Liqiong Guo |
| author_facet | Bibo Yuan Citlalli Osorio-Yáñez Junkai Fang Lei Zhao Ander Wilson Marco Sanchez-Guerra Hongbin Liu Peng-Hui Li Liqiong Guo |
| author_sort | Bibo Yuan |
| collection | DOAJ |
| description | Abstract Although occupational exposure to radiation and organic solvents has been proven to increase the chance of developing thyroid disease, one of the leading endocrine disorders, much less is known about the potential risk factor of vibration exposure. Thus, this study aimed to examine the relationships between occupational exposure to radiation, organic solvents and vibration, and thyroid disease risk and thyroid-stimulating hormone (TSH) levels by utilizing data sets from Project ELEFANT, which comprises 124,286 participants from Tianjin, China. We reviewed the medical records, including the thyroid disease history, of young adult participants and measured the TSH levels in the females via automated immunometric assay. Logistic models adjusted for confounders revealed significant associations between exposure to radiation (odds ratio [OR]: 1.73; 95% confidence interval [CI]: 1.1–2.7), organic solvents (OR: 2.0; 95% CI: 1.3–2.9) and vibration (OR: 4.4; 95% CI: 2.0–8.75), and an increased risk of thyroid disease. Additionally, the TSH concentrations in the female participants (median: 1.95; 95% CI: 2.45–2.77) displayed a correlation exclusively with vibration exposure (β: 2.80; 95% CI: 1.07–4.54). Our results show, for the first time, that vibration exposure is associated with an increased risk of thyroid disease and elevated TSH levels. If these findings are confirmed in other cohorts, thyroid examinations should be conducted for individuals exposed to vibration in the workplace. |
| format | Article |
| id | doaj-art-2a03bcbd90c44ea2ab635a638177f838 |
| institution | Kabale University |
| issn | 1680-8584 2071-1409 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Springer |
| record_format | Article |
| series | Aerosol and Air Quality Research |
| spelling | doaj-art-2a03bcbd90c44ea2ab635a638177f8382025-02-09T12:21:35ZengSpringerAerosol and Air Quality Research1680-85842071-14092021-06-0121911010.4209/aaqr.210085Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANTBibo Yuan0Citlalli Osorio-Yáñez1Junkai Fang2Lei Zhao3Ander Wilson4Marco Sanchez-Guerra5Hongbin Liu6Peng-Hui Li7Liqiong Guo8Department of Gynecology and Obstetrics, Tianjin Medical University General HospitalInstituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de MéxicoTianjin Institute of Medical & Pharmaceutical SciencesInstitute of Disaster and Emergency Medicine, Tianjin UniversityDepartment of Statistics, Colorado State UniversityDepartment of Developmental Neurobiology, National Institute of PerinatologyTianjin Institute of Medical & Pharmaceutical SciencesSchool of Environmental Science and Safety Engineering, Tianjin University of TechnologyInstitute of Disaster and Emergency Medicine, Tianjin UniversityAbstract Although occupational exposure to radiation and organic solvents has been proven to increase the chance of developing thyroid disease, one of the leading endocrine disorders, much less is known about the potential risk factor of vibration exposure. Thus, this study aimed to examine the relationships between occupational exposure to radiation, organic solvents and vibration, and thyroid disease risk and thyroid-stimulating hormone (TSH) levels by utilizing data sets from Project ELEFANT, which comprises 124,286 participants from Tianjin, China. We reviewed the medical records, including the thyroid disease history, of young adult participants and measured the TSH levels in the females via automated immunometric assay. Logistic models adjusted for confounders revealed significant associations between exposure to radiation (odds ratio [OR]: 1.73; 95% confidence interval [CI]: 1.1–2.7), organic solvents (OR: 2.0; 95% CI: 1.3–2.9) and vibration (OR: 4.4; 95% CI: 2.0–8.75), and an increased risk of thyroid disease. Additionally, the TSH concentrations in the female participants (median: 1.95; 95% CI: 2.45–2.77) displayed a correlation exclusively with vibration exposure (β: 2.80; 95% CI: 1.07–4.54). Our results show, for the first time, that vibration exposure is associated with an increased risk of thyroid disease and elevated TSH levels. If these findings are confirmed in other cohorts, thyroid examinations should be conducted for individuals exposed to vibration in the workplace.https://doi.org/10.4209/aaqr.210085VibrationOrganic solventsRadiationThyroid diseaseThyroid-stimulating hormone |
| spellingShingle | Bibo Yuan Citlalli Osorio-Yáñez Junkai Fang Lei Zhao Ander Wilson Marco Sanchez-Guerra Hongbin Liu Peng-Hui Li Liqiong Guo Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT Aerosol and Air Quality Research Vibration Organic solvents Radiation Thyroid disease Thyroid-stimulating hormone |
| title | Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT |
| title_full | Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT |
| title_fullStr | Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT |
| title_full_unstemmed | Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT |
| title_short | Effect of Radiation, Organic Solvents and Vibration Occupational Exposure on the Thyroid Disease: Results from Project ELEFANT |
| title_sort | effect of radiation organic solvents and vibration occupational exposure on the thyroid disease results from project elefant |
| topic | Vibration Organic solvents Radiation Thyroid disease Thyroid-stimulating hormone |
| url | https://doi.org/10.4209/aaqr.210085 |
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