Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp
Background. Divergent differentiation in malignant melanoma is a rare phenomenon, which can lead to delayed diagnosis or misdiagnosis, impacting upon patient treatment and outcome, as well as the understanding of tumour behaviour. Case. We present the case of a large long-standing tumour on the scal...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/1063569 |
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| _version_ | 1849307822686208000 |
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| author | Colin S. Alderson Helen E. Douglas Rebecca Rollett Bipin Mathew Paolo Matteucci |
| author_facet | Colin S. Alderson Helen E. Douglas Rebecca Rollett Bipin Mathew Paolo Matteucci |
| author_sort | Colin S. Alderson |
| collection | DOAJ |
| description | Background. Divergent differentiation in malignant melanoma is a rare phenomenon, which can lead to delayed diagnosis or misdiagnosis, impacting upon patient treatment and outcome, as well as the understanding of tumour behaviour. Case. We present the case of a large long-standing tumour on the scalp of a 72-year-old female patient, which when excised and examined histologically was revealed to be a nodular malignant melanoma displaying chondrosarcomatous differentiation. Foci suggestive of lentigo maligna were also present. Rapid metastatic spread of the tumour was observed shortly after the primary resection. Discussion. To our knowledge, this is the first reported case in the literature of chondrosarcomatous differentiation in a lentigo maligna melanoma. The clinical and histopathological details and images of this case are presented alongside a discussion regarding such tumours and patterns of similar tumour behaviour. |
| format | Article |
| id | doaj-art-29df3bb7d3da412792b64b04dbf46d99 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-29df3bb7d3da412792b64b04dbf46d992025-08-20T03:54:37ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/10635691063569Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the ScalpColin S. Alderson0Helen E. Douglas1Rebecca Rollett2Bipin Mathew3Paolo Matteucci4Leeds Teaching Hospitals Trust, Leeds, UKCastle Hill Hospital, East Yorkshire, UKCastle Hill Hospital, East Yorkshire, UKLeeds Teaching Hospitals Trust, Leeds, UKCastle Hill Hospital, East Yorkshire, UKBackground. Divergent differentiation in malignant melanoma is a rare phenomenon, which can lead to delayed diagnosis or misdiagnosis, impacting upon patient treatment and outcome, as well as the understanding of tumour behaviour. Case. We present the case of a large long-standing tumour on the scalp of a 72-year-old female patient, which when excised and examined histologically was revealed to be a nodular malignant melanoma displaying chondrosarcomatous differentiation. Foci suggestive of lentigo maligna were also present. Rapid metastatic spread of the tumour was observed shortly after the primary resection. Discussion. To our knowledge, this is the first reported case in the literature of chondrosarcomatous differentiation in a lentigo maligna melanoma. The clinical and histopathological details and images of this case are presented alongside a discussion regarding such tumours and patterns of similar tumour behaviour.http://dx.doi.org/10.1155/2016/1063569 |
| spellingShingle | Colin S. Alderson Helen E. Douglas Rebecca Rollett Bipin Mathew Paolo Matteucci Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp Case Reports in Medicine |
| title | Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp |
| title_full | Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp |
| title_fullStr | Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp |
| title_full_unstemmed | Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp |
| title_short | Chondrosarcomatous Differentiation in a Large Malignant Melanoma of the Scalp |
| title_sort | chondrosarcomatous differentiation in a large malignant melanoma of the scalp |
| url | http://dx.doi.org/10.1155/2016/1063569 |
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