Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case report
Insulinoma is a rare but challenging-to-diagnose pancreatic neuroendocrine tumor, often presenting with recurrent spontaneous hypoglycemia. Surgical resection remains the definitive treatment; however, accurate preoperative localization is critical for optimizing surgical outcomes and avoiding unnec...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-08-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325003607 |
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| author | Quang Trung Nguyen, BSc Van Diep Pham, BSc Quoc Dat Tran, BSc Quang Long Le, BSc Ngoc Cuong Nguyen, PhD Tuan Linh Le, PhD |
| author_facet | Quang Trung Nguyen, BSc Van Diep Pham, BSc Quoc Dat Tran, BSc Quang Long Le, BSc Ngoc Cuong Nguyen, PhD Tuan Linh Le, PhD |
| author_sort | Quang Trung Nguyen, BSc |
| collection | DOAJ |
| description | Insulinoma is a rare but challenging-to-diagnose pancreatic neuroendocrine tumor, often presenting with recurrent spontaneous hypoglycemia. Surgical resection remains the definitive treatment; however, accurate preoperative localization is critical for optimizing surgical outcomes and avoiding unnecessary extensive pancreatic resection. We report a case of a 57-year-old female with recurrent hypoglycemia, whose lesion was undetectable using conventional ultrasound, computed tomography (CT), and standard magnetic resonance imaging (MRI). However, small field-of-view diffusion-weighted imaging (sFOV DWI) successfully identified a 13 × 10 mm pancreatic lesion between the body and tail, with imaging characteristics consistent with a pancreatic neuroendocrine tumor. The patient underwent successful surgical resection, with histopathological confirmation of insulinoma, leading to complete resolution of symptoms postoperatively. This case highlights the utility of sFOV DWI in detecting small pancreatic lesions that may be missed by conventional imaging techniques. Its application in challenging cases could significantly improve diagnostic accuracy and guide surgical planning. |
| format | Article |
| id | doaj-art-29d6209620474a719f7794e3aeefd2fa |
| institution | Kabale University |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-29d6209620474a719f7794e3aeefd2fa2025-08-20T03:26:38ZengElsevierRadiology Case Reports1930-04332025-08-012083703370910.1016/j.radcr.2025.04.059Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case reportQuang Trung Nguyen, BSc0Van Diep Pham, BSc1Quoc Dat Tran, BSc2Quang Long Le, BSc3Ngoc Cuong Nguyen, PhD4Tuan Linh Le, PhD5Corresponding author.; Radiology Center, Hanoi Medical University Hospital, Hanoi, VietnamRadiology Center, Hanoi Medical University Hospital, Hanoi, VietnamRadiology Center, Hanoi Medical University Hospital, Hanoi, VietnamRadiology Center, Hanoi Medical University Hospital, Hanoi, VietnamRadiology Center, Hanoi Medical University Hospital, Hanoi, VietnamRadiology Center, Hanoi Medical University Hospital, Hanoi, VietnamInsulinoma is a rare but challenging-to-diagnose pancreatic neuroendocrine tumor, often presenting with recurrent spontaneous hypoglycemia. Surgical resection remains the definitive treatment; however, accurate preoperative localization is critical for optimizing surgical outcomes and avoiding unnecessary extensive pancreatic resection. We report a case of a 57-year-old female with recurrent hypoglycemia, whose lesion was undetectable using conventional ultrasound, computed tomography (CT), and standard magnetic resonance imaging (MRI). However, small field-of-view diffusion-weighted imaging (sFOV DWI) successfully identified a 13 × 10 mm pancreatic lesion between the body and tail, with imaging characteristics consistent with a pancreatic neuroendocrine tumor. The patient underwent successful surgical resection, with histopathological confirmation of insulinoma, leading to complete resolution of symptoms postoperatively. This case highlights the utility of sFOV DWI in detecting small pancreatic lesions that may be missed by conventional imaging techniques. Its application in challenging cases could significantly improve diagnostic accuracy and guide surgical planning.http://www.sciencedirect.com/science/article/pii/S1930043325003607InsulinomaCTMRISmall field-of-view DWIPancreatic neuroendocrine tumor |
| spellingShingle | Quang Trung Nguyen, BSc Van Diep Pham, BSc Quoc Dat Tran, BSc Quang Long Le, BSc Ngoc Cuong Nguyen, PhD Tuan Linh Le, PhD Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case report Radiology Case Reports Insulinoma CT MRI Small field-of-view DWI Pancreatic neuroendocrine tumor |
| title | Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case report |
| title_full | Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case report |
| title_fullStr | Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case report |
| title_full_unstemmed | Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case report |
| title_short | Improved detection and localization of insulinoma using small field-of-view diffusion-weighted MRI: A case report |
| title_sort | improved detection and localization of insulinoma using small field of view diffusion weighted mri a case report |
| topic | Insulinoma CT MRI Small field-of-view DWI Pancreatic neuroendocrine tumor |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325003607 |
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