Fascia-derived stem cells enhance fat graft retention by promoting vascularization through the HMOX1-HIF-1α pathway

Fascia-derived stem cells enhance fat graft retention by promoting vascularization through the HMOX1-HIF-1α pathway

Abstract Background Adipose tissue is a widely used autologous soft tissue filler in plastic surgery, particularly for volumetric restoration in cases of soft tissue deficiency. However, effectively controlling the retention rate of transplanted fat remains a major challenge. Therefore, this study a...

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Main Authors: Guo Chen, Jie Long, Yuge Zhang, Xuhua Zhou, Botao Gao, Zijin Qin, Yuhan Zhu, Binyu Song, Ziwei Cui, Zhangzi liu, Man Xu, Zhou Yu, Baoqiang Song, Ziang Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Stem Cell Research & Therapy
Subjects:
Superficial Fascia
Stem cells
Vascularization
Graft Retention
HMOX1
HIF-α
Online Access:https://doi.org/10.1186/s13287-025-04204-w
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