NLRP3 in the dorsal raphe nucleus manipulates the depressive-like behaviors

NLRP3 in the dorsal raphe nucleus manipulates the depressive-like behaviors

Major depressive disorder is one of the most common psychiatric disorders, and the Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome plays an important role in depression. Dorsal raphe nucleus (DRN), as the main origin of producing serotonin in the brain, is an important functi...

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Bibliographic Details
Main Authors: Junchao Cai, Jiarong Zhao, Rui Peng, Heming Yu, Yong He, Qigang Zhou, Yue Wang, Peng Xie
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Brain Research Bulletin
Subjects:
Depression
NLRP3
Dorsal raphe nucleus
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025002175
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