Multiple Roles of Myd88 in the Immune Response to the Plague F1-V Vaccine and in Protection against an Aerosol Challenge of Yersinia pestis CO92 in Mice
The current candidate vaccine against Yersinia pestis infection consists of two subunit proteins: the capsule protein or F1 protein and the low calcium response V protein or V-antigen. Little is known of the recognition of the vaccine by the host’s innate immune system and how it affects the acquir...
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| Main Authors: | Jennifer L. Dankmeyer, Randy L. Fast, Christopher K. Cote, Patricia L. Worsham, David Fritz, Diana Fisher, Steven J. Kern, Tod Merkel, Carsten J. Kirschning, Kei Amemiya |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2014/341820 |
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